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Title: US6190861: Molecular sequences of swine retroviruses method of using
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Country: US United States of America

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127 pages

 
Inventor: Fishman, Jay A.; Wellesley, MA

Assignee: The General Hospital Corporation, Boston, MA
other patents from GENERAL HOSPITAL CORPORATION (218835) (approx. 654)
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Published / Filed: 2001-02-20 / 1996-12-13

Application Number: US1996000766528

IPC Code: Advanced: A01K 67/027; C07K 14/15; C12N 7/00; C12N 15/09; C12N 15/85; C12N 15/867; C12Q 1/68; C12Q 1/70;
Core: C07K 14/005; more...
IPC-7: C07H 19/00; C07H 21/04; C12Q 1/68; C12Q 1/70;

ECLA Code: C07K14/15; C12N7/00; C12N15/85A2; C12N15/867; C12Q1/68M10; C12Q1/70B2; K01K227/10S; K01K267/02; K01K267/02B; K01K267/03D; M07K203/00; M07K205/00; M07K207/00; M07K213/00; M07K213/02; M07K215/00; M12N205/00; M12N740/03C; M12Q1/68B6; K01K217/05; K01K217/07B;

U.S. Class: Current: 435/005; 435/006; 536/022.1; 536/023.1; 536/023.5; 536/024.3; 536/024.31;
Original: 435/005; 435/006; 536/022.1; 536/023.1; 536/023.5; 536/024.3; 536/024.31;

Field of Search: 435/5;6 536/22.1,23.1,23.5,24.3,24.31

Priority Number:
1996-12-13  US1996000766528
1995-12-14  US1995000572645

Abstract:     Purified nucleic acid which can specifically hybridize with the sequence of swine retroviruses.

Attorney, Agent or Firm: Hale and Dorr LLP ;

Primary / Asst. Examiners: Riley, Jezia;

Maintenance Status: CC Certificate of Correction issued
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Related Applications: Go to Result Set: 3 patent(s) that list this one as related
Application Number Filed Patent Pub. Date  Title
US1995000572645 1995-12-14       


       
Parent Case:     This application is a continuation-in-part of U.S. Ser. No. 08/572,645, filed Dec. 14, 1995, now abandoned, which is hereby incorporated by reference.

Designated Country: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE  AU CA EP JP 

Family: Show 21 known family members

First Claim:
Show all 93 claims
What is claimed is:     1. A method for screening a cell or a tissue for the presence or expression of a swine or miniature swine retrovirus comprising:
  • contacting a target nucleic acid from the cell or tissue with a second nucleic acid selected from the group of: a sequence which can specifically hybridize to the sequence of SEQ ID NO:1, or its complement of the same length; a sequence which can specifically hybridize to the sequence of SEQ ID NO:2, or its complement of the same length; a sequence which can specifically hybridize to tie sequence of SEQ ID NO:3, or its complement of the same length; a nucleic acid which can specifically hybridize to a sense or antisense sequence which encodes a gag protein, said sense or antisense sequence being selected from the group consisting of gag-encoding nucleotides of SEQ ID NO:1, gag-encoding nucleotides of SEQ ID NO:2, and gag-encoding nucleotides of SEQ ID NO:3; a nucleic acid which can specifically hybridize to a sense or antisense sequence from nucleotides 2452-4839 or nucleotides 3112-4693 of SEQ ID NO:1, nucleotides 598-2169 of SEQ ID NO:2, or nucleotides 585-2156, of SEQ ID NO:3; a nucleic acid which can specifically hybridize to a sense or antisense sequence which encodes a pol protein, said sense pol antisense sequence being selected from the group consisting of pol-encoding nucleotides of SEQ ID NO:1, pol-encoding nucleotides of SEQ ID NO:2, and pol-encoding nucleotides of SEQ ID NO:3; a nucleic acid which can specifically hybridize to a sense or antisense sequence from nucleotides 4871-8060 of SEQ ID NO:1, nucleotides 2320-4737 of SEQ ID NO:2, or nucleotides 2307-5741 of SEQ ID NO:3; a nucleic acid which can specifically hybridize to a sense or antisense sequence which encodes an env protein, said sense or antisense sequence being selected from the group consisting of env-encoding nucleotides of SEQ ID NO:1, env-encoding nucleotides of SEQ ID NO-2, and env-encoding nucleotides of SEQ ID NO:3; a nucleic acid which can specifically hybridize to a sense or antisense sequence from nucleotides 2-1999 or nucleotides 86-1999 of SEQ ID NO:1, nucleotides 4738-6722 of SEQ ID NO:2, or nucleotides 5620-7533 of SEQ ID NO:3, under conditions in which hybridization can occur, hybridization being indicative of the presence or expression of an endogenous swine or miniature swine retrovirus or retroviral sequence in the cell or tissue.


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Forward References: Show 5 U.S. patent(s) that reference this one

       
U.S. References: Go to Result Set: All U.S. references   |  Forward references (5)   |   Backward references (2)   |   Citation Link

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Publication Date IPC Code Assignee   Title
Buy PDF- 49pp WO9304169 1993-03  C12N 15/00 BERNS, Anton GENE TARGETING IN ANIMAL CELLS USING ISOGENIC DNA CONSTRUCTS 


Other Abstract Info: DERABS C2001-256211

Other References:
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  • Bouillant et al., "Type C virus production by a continuous line of pig oviduct cells (PFT)", J. Gen. Virol. 27:173 (1975). (8 pages) Cited by 2 patents
  • Bouillant et al., "Ultrastructural comparison of Oncovirinae (type C), Spumavirinae, and Lentivirinae: three subfamilies of Retroviridae found in form animals", J. Nat. Cancer Institute 72:1075 (1984). (10 pages) Cited by 4 patents
  • Busse et al., "Further investigations on the porcine lymphoma C-type particle (PLCP) and the possible biological significance of the virus in pigs", Ann. Rech. Vet. 5(4):651-658 (1978). (8 pages) Cited by 2 patents
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  • Eron, J.J. et al. "Susceptibility testing by polymerase chain reaction DNA quantitation: A method to measure durg resistance of human immunodeficiency virus type 1 isolates" PNAS USA 89:3241-3245 (1992). (5 pages) Cited by 11 patents [ISI abstract]
  • Fishman, J.A. "Miniature swine as organ donors for man: Strategies for prevention of xenotransplant-associated infections" Xenotransplantation 1:47-57 (1994).
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  • Frazier, "Evidence for retrovirus in miniature swine with radiation-induced leukemia or metaplasia" Arch. of Virology 83:83-97 (1985). (15 pages) Cited by 2 patents
  • Frazier et al., "Virus association with 90 Sr Induced leukemia of miniature swine" Comparative Leukemia Res. 36:440-445 (1969).
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  • Kaeffer et al., "Histocompatible miniature boar model: selection of transformed cell lines of B and T lineages producing retrovirus" Int. J. Cancer 46:481-488 (1990). (8 pages) Cited by 2 patents
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  • Phan-Thanh, L. et al. "Porcine retrovirus: optimal conditions for its biochemical detection" Arch. Virol. 123(3-4):255-265 (1992). (11 pages) Cited by 2 patents [ISI abstract]
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  • Suzuka, I. et al. "Molecular cloning of unintegrated closed circular DNA of porcine retrovirus" FEBS 198(2):339-343 (1986). (5 pages) Cited by 2 patents
  • Suzuka, I. et al. "Some characteristics of a porcine retrovirus from a cell line derived from swine malignant lymphomas" FEBS 183(1):124-128 (1985). (5 pages) Cited by 2 patents
  • Suzuki et al., "Production and characterization of monoclonal antibodies which affect RNA-dependent DNA polymerase activity of porcine retrovirus reverse transcriptase" Jpn J Vet Sci 50:295-297 (1988). (3 pages) Cited by 2 patents
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  • Te Riele, H. et al. "Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs" PNAS USA 89:5128-5132 (1992). (5 pages) Cited by 15 patents [ISI abstract]
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  • Bowes, "Localization of a retroviral element within the rd gene coding the Beta Subunit of cGMP phosphodiesterase", PNAS USA 90:2955-2959 (1993). (5 pages) [ISI abstract]
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  • Continuity Data:
    Application Number Filed Notes

    US1996000766528 1996-12-13  is a related to the prior publication
         US20040185435A1 issued 2004-09-23  Molecular sequence of swine retrovirus and methods of use

    12334602   is a continuation of
    US2003000723552  2003-11-26
         US7465573 issued 2008-12-16   Molecular sequence of swine retrovirus and methods of use

    US2003000723552 2003-11-26  is a division of
    US2000000661858  2000-09-14   (granted)
         US6699663 issued 2004-03-02   Molecular sequence of swine retrovirus

    US2003000723552   is a division of
    US2000000661858  2000-09-14
         US6699663 issued 2004-03-02   Molecular sequence of swine retrovirus

    US2000000661858 2000-09-14  is a division of
    >US1996000766528<  1996-12-13   (granted)
         US6190861 issued 2001-02-20   Molecular sequence of swine retrovirus and methods of use

    US2000000661858   is a division of
    >US1996000766528<  1996-12-13
         US6190861 issued 2001-02-20   Molecular sequence of swine retrovirus and methods of use

    >US1996000766528< 1996-12-13  is a continuation in part of
    US1995000572645  1995-12-14   (abandoned)

    >US1996000766528<   is a continuation in part of
    US1995000572645  1995-12-14   (abandoned)


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