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Title: US7375404: Fabrication and integration of polymeric bioMEMS
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Country: US United States of America

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Inventor: Park, Jung Jin; Beltsville, MD, United States of America
Ghodssi, Reza; Rockville, MD, United States of America
Rubloff, Gary W.; Clarksville, MD, United States of America
Kastantin, Mark Joseph; Goleta, CA, United States of America
Li, Sheng; Greenbelt, MD, United States of America
Wu, Li-Qun; N. Potomac, MD, United States of America
Yi, Hyunmin; Beltsville, MD, United States of America
Valentine, Theresa Michelle; Potomac, MD, United States of America

Assignee: University of Maryland Biotechnology Institute, Baltimore, MD, United States of America
University of Maryland, College Park, College Park, MD, United States of America
other patents from UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (731396) (approx. 38)
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Published / Filed: 2008-05-20 / 2004-12-03

Application Number: US2004000003005

IPC Code: Advanced: B01L 3/00; B81B 7/00; B81C 3/00; H01L 27/14; H01L 29/86;
Core: H01L 29/66; more...

ECLA Code: B01L3/00C6M; B81B7/00P8; B81C3/00D; L01L200/00A8M; L01L200/00M; L01L300/00C2; L01L300/00D4E; L01L300/00G2; L01L300/00G4C; L01L300/00G12; L81B201/05Z; L81D1/00;

U.S. Class: 257/414; 257/040;

Field of Search: 257/414,415,40

Government Interest: GOVERNMENT LICENSING CLAUSE
    The U.S. Government has a paid-up license in this invention and the right in limited circumstances to require the patent owner to license others on reasonable terms as provided for by the terms of Grant No. DMR 4-32291 awarded by the National Science Foundation.

Priority Number:
2004-12-03  US2004000003005
2003-12-05  US2003000527394P
2004-06-09  US2004000578207P

Abstract:     A micro-electro-mechanical system (MEMS) device is provided, along with means for its fabrication and operation for microfluidic and/or biomicrofluidic applications. The MEMS device includes a substrate, optional electrodes on the substrate, a patterned structure on the substrate, the patterned structure having a fluidic microchannel aligned with one or more of the optional electrodes, an encapsulation membrane covering the microchannel, and an optional reactive layer deposited over the electrode in the microchannel. MEMS devices of preferred embodiments permit a leak-tight seal to be formed around the microchannel and fluidic interconnects established for robust operation of fluidics-based processes. MEMS devices of other preferred embodiments permit reversible attachment and separation of the encapsulation membrane relative to the patterned structure.

Attorney, Agent or Firm: Edell, Shapiro & Finnan, LLC ; Auerbach, Jeffrey I. ; Cohan, June E. ;

Primary / Asst. Examiners: Nguyen, Tuan H.;

INPADOC Legal Status: None          Buy Now: Family Legal Status Report

Parent Case: RELATED APPLICATIONS
    This application claims the benefit of priority of U.S. provisional application Ser. No. 60/527,394 filed in the U.S. Patent & Trademark Office on Dec. 5, 2003 entitled “Fabrication and Integration of Polymeric BioMEMS,” the complete disclosure of which is incorporated herein by reference.
    This application also claims the benefit of priority of U.S. provisional application Ser. No. 60/578,207 filed in the U.S. Patent & Trademark Office on Jun. 9, 2004 entitled “Micro-Knife-Edge Technique for Sealing of Microfluidic Systems,” the complete disclosure of which is incorporated herein by reference.

Family: Show 2 known family members

First Claim:
Show all 40 claims
    1. A micro-electro-mechanical system (MEMS) device, comprising:

a substrate;

a patterned structure on the substrate, the patterned structure having a microchannel; and

an encapsulation layer covering the microchannel, the encapsulation layer being reversibly attachable and separable with respect to the patterned structure;

wherein:

the patterned structure comprises an epoxy; and

the encapsulation layer comprises polydimethylsiloxane.



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U.S. References: Go to Result Set: All U.S. references   |  No patents reference this one   |   Backward references (17)   |   Citation Link

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Buy PDF- 12pp US4148689  1979-04 Hino et al.  Sanraku-Ocean Co., Ltd. Immobilization of microorganisms in a hydrophilic complex gel
Buy PDF- 8pp US5015576  1991-05 Nilsson et al.   Macroporous particles for cell cultivation or chromatography
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Foreign References:
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PDF
Publication Date IPC Code Assignee   Title
  JP 239 396 1997-09       
  JP10310041 1998-11       
Buy PDF- 47pp WO0011038 2000-03  C08B 37/00 KUMAR GUNEET MODIFIED CHITOSAN POLYMERS AND ENZYMATIC METHODS FOR THE PRODUCTION THEREOF 
  WO 2004/018741 2004-03       


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  • Continuity Data:
    Application Number Filed Notes

    US2004000003005 2004-12-03  is a related to the prior publication
         US20050230767A1 issued 2005-10-20  Fabrication and integration of polymeric bioMEMS

    US2004000003005 2004-12-03  is a non-provisional of provisional
    US2004000578207P  2004-06-09

    US2004000003005 2004-12-03  is a non-provisional of provisional
    US2003000527394P  2003-12-05


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