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Title: |
US4837029:
Low foaming, aqueously homogenizable rifampin composition
[ Derwent Title ]

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Country: |
US United States of America

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Inventor: |
Olsen, James L.; Chapel Hill, NC

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Assignee: |
Carolina Medical Products, Inc., Chapel Hill, NC
other patents from CAROLINA MEDICAL PRODUCTS, INC. (90230) (approx. 3)
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Published / Filed: |
1989-06-06
/ 1987-04-06

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Application Number: |
US1987000034767

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IPC Code: |
Advanced:
A61K 9/00;
A61K 9/20;
A61K 9/48;
A61K 31/495;
A61K 47/20;
A61K 47/34;
Core:
more...
IPC-7:
A61K 9/48;
A61K 31/74;

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U.S. Class: |
Current:
514/252.13;
424/464;
514/063;
Original:
424/451;
424/464;
424/078;
514/255;

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Field of Search: |
424/078,451,464

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Priority Number: |
| 1987-04-06 |
US1987000034767 |

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Abstract: |
An antibiotic composition comprising rifampin, a dimethyl polysiloxane polymer, and a cationic or non-ionic surfactant, wherein the rifampin, dimethyl polysiloxane polymer, and surfactant are present in relative amounts such that the composition is aqueously homogenizable with low foaming.
Also disclosed is a method of antibiotic treatment wherein such composition is administered orally, either in a solid dosage form or in an aqueous medium.

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Attorney, Agent or Firm: |
Barber, Lynn E. ;
Hultquist, Steven J. ;

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Primary / Asst. Examiners: |
Schofer, Joseph L.; Kulkosky, Peter F.

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INPADOC Legal Status: |
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Family: |
None

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First Claim:
Show all 20 claims |
What is claimed is:
1. A readily aqueously dispersable antibiotic composition devoid of any enclosing web structure and/or chelating agents, said composition consisting essentially of rifampin, a dimethyl polysiloxane polymer, and a pharmaceutically acceptable cationic or non-ionic surfactant, wherein the rifampin, dimethyl polysiloxane polymer, and pharamceutically acceptable cationic or non-ionic surfactant, are each present in amounts such that the composition is aqueously homogenizable with low foaming incident thereto.

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Background / Summary: |
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Drawing Descriptions: |
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Description: |
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Forward References: |
Show 4 U.S. patent(s) that reference this one

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