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Title: US4837029: Low foaming, aqueously homogenizable rifampin composition
[ Derwent Title ]


Country: US United States of America

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6 pages

 
Inventor: Olsen, James L.; Chapel Hill, NC

Assignee: Carolina Medical Products, Inc., Chapel Hill, NC
other patents from CAROLINA MEDICAL PRODUCTS, INC. (90230) (approx. 3)
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Published / Filed: 1989-06-06 / 1987-04-06

Application Number: US1987000034767

IPC Code: Advanced: A61K 9/00; A61K 9/20; A61K 9/48; A61K 31/495; A61K 47/20; A61K 47/34;
Core: more...
IPC-7: A61K 9/48; A61K 31/74;

U.S. Class: Current: 514/252.13; 424/464; 514/063;
Original: 424/451; 424/464; 424/078; 514/255;

Field of Search: 424/078,451,464

Priority Number:
1987-04-06  US1987000034767

Abstract: An antibiotic composition comprising rifampin, a dimethyl polysiloxane polymer, and a cationic or non-ionic surfactant, wherein the rifampin, dimethyl polysiloxane polymer, and surfactant are present in relative amounts such that the composition is aqueously homogenizable with low foaming. Also disclosed is a method of antibiotic treatment wherein such composition is administered orally, either in a solid dosage form or in an aqueous medium.

Attorney, Agent or Firm: Barber, Lynn E. ; Hultquist, Steven J. ;

Primary / Asst. Examiners: Schofer, Joseph L.; Kulkosky, Peter F.

INPADOC Legal Status: Show legal status actions

Family: None

First Claim:
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What is claimed is:     1. A readily aqueously dispersable antibiotic composition devoid of any enclosing web structure and/or chelating agents, said composition consisting essentially of rifampin, a dimethyl polysiloxane polymer, and a pharmaceutically acceptable cationic or non-ionic surfactant, wherein the rifampin, dimethyl polysiloxane polymer, and pharamceutically acceptable cationic or non-ionic surfactant, are each present in amounts such that the composition is aqueously homogenizable with low foaming incident thereto.

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Forward References: Show 4 U.S. patent(s) that reference this one

       
U.S. References: Go to Result Set: All U.S. references   |  Forward references (4)   |   Backward references (4)   |   Citation Link

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Patent  Pub.Date  Inventor Assignee   Title
Get PDF - 5pp US4195084  1980-03 Ong  Eli Lilly and Company Taste-stable aqueous pharmaceutical suspension of tall oil sitosterols and a method for the preparation thereof
Get PDF - 27pp US4332789  1982-06 Mlodozeniec  Hoffmann-La Roche Inc. Pharmaceutical unit dosage forms
Get PDF - 4pp US4613496  1986-09 Kopf  Ciba-Geigy Corporation Pharmaceutical capsules of Rifampicin with uniform elution properties
Get PDF - 7pp US4687662  1987-08 Schobel  Warner-Lambert Company Therapeutic effervescent composition
       
Foreign References: None

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