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 Title: |
US5314685:
Anhydrous formulations for administering lipophilic agents
[ Derwent Title ]
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| Country: |
US United States of America
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| Inventor: |
Tyle, Praveen; San Diego, CA
Freebern, Kenneth R.; San Diego, CA
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| Assignee: |
Agouron Pharmaceuticals, Inc., San Diego, CA
other patents from AGOURON PHARMACEUTICALS, INC. (701577) (approx. 97)
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| Published / Filed: |
1994-05-24
/ 1992-05-11
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| Application Number: |
US1992000881085
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| IPC Code: |
Advanced:
A61K 9/06;
A61K 9/08;
A61K 45/08;
Core:
A61K 45/00;
more...
IPC-7:
A61K 7/02;
A61K 31/74;
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| ECLA Code: |
A61K9/06;
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| U.S. Class: |
Current:
424/401;
514/937;
Original:
424/401;
514/937;
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| Field of Search: |
424/401,78.03,78.05,78.06,78.07
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| Priority Number: |
| 1992-05-11 |
US1992000881085 |
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| Abstract: |
Anhydrous formulations useful for administering lipophilic, pharmaceutically active agents to hosts in need of such treatment processes for preparing these formulations, pharmaceutical compositions based upon these formulations, and the use of these formulations to administer lipophilic, pharmaceutically active agents to a host. The lipophilic agent to be administered is solubilized in a hydrophilic vehicle which makes up at least part of the anhydrous formulation. Preferably, the lipophilic agent is present in the hydrophilic vehicle in a supersaturated or near saturated amount. Preferred pharmaceutical compositions based upon the formulations according to the present invention are useful in treating skin dermatoses such as psoriasis.
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| Attorney, Agent or Firm: |
Finnegan, Henderson, Farabow, Garrett & Dunner ;
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| Primary / Asst. Examiners: |
Page, Thurman K.; Azpuru, C.
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| Maintenance Status: |
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| INPADOC Legal Status: |
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| Designated Country: |
AT AU BB BG BR CA CH CZ DE DK EP ES FI GB HU JP KP KR KZ LK LU MG MN MW NL NO NZ OA PL PT RO RU SD SE SK UA VN
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| Family: |
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First Claim:
Show all 4 claims |
We claim:
1. A method of making an anhydrous formulation, comprising the steps of:
- (a) preparing an anhydrous hydrophilic phase comprising least one hydrophilic vehicle suitable for solubilizing at least one lipophilic, pharmaceutically active agent for administering to a host in need of treatment;
- (b) preparing an oily phase comprising at least one oily component which is partially miscible with said at least one hydrophilic vehicle; and
- (c) combining said oily phase with said anhydrous hydrophilic phase to form said anhydrous formulation.
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| Background / Summary: |
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| Drawing Descriptions: |
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| Description: |
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| Forward References: |
Show 24 U.S. patent(s) that reference this one
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