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Title: |
US6251370:
Tissue adhesive suitable for spray application
[ Derwent Title ]

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Country: |
US United States of America

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Inventor: |
Uchida, Takanori; Kumamoto, Japan
Kaetsu, Hiroshi; Nishigoushi-machi, Japan
Fukunaga, Nobuto; Tamana, Japan
Shinya, Noriko; Kumamoto, Japan
Sakamoto, Takahiro; Goushi-machi, Japan

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Assignee: |
Juridical Foundation The Chemosero Therapeutic Research Institute, Kumamoto, Japan
other patents from JURIDICAL FOUNDATION, THE CHEMO-SERO-THERAPEUTIC RESEARCH IN (299155) (approx. 66)
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Published / Filed: |
2001-06-26
/ 1999-04-28

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Application Number: |
US1999000299916

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IPC Code: |
Advanced:
A61B 17/00;
A61L 24/10;
Core:
A61L 24/00;
more...
IPC-7:
A61L 9/04;

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ECLA Code: |
A61B17/00L; A61L24/10F;

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U.S. Class: |
Current:
424/045;
424/094.64;
424/445;
514/822;
530/303;
530/380;
530/381;
530/382;
530/384;
Original:
424/045;
424/094.64;
424/445;
514/822;
530/380;
530/381;
530/382;
530/384;
530/303;

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Field of Search: |
424/045,94.64,445
530/300,381,382,303,384
514/822

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Priority Number: |
| 1996-03-15 |
JP1996000087566 |

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Abstract: |
An adhesive for tissue capable of uniformly forming a high concentration of fibrin so as to provide a high closing effect is disclosed. The adhesive for tissue comprises a fibrinogen solution and a thrombin solution which solutions are separated from each other. The adhesive is to be mixed and spray coated together with a sterile gas and has a volume ratio of the fibrinogen solution to the thrombin solution of about 2:1 to 10:1. This adhesive is to be sprayed together with a sterile gas for the adhesion or closing of living tissue of a human being or animal.

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Attorney, Agent or Firm: |
Oblon, Spivak, McClelland, Maier & Neustadt, P.C. ;

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Primary / Asst. Examiners: |
Page, Thurman K.; Channavajjala, Lakshmi

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INPADOC Legal Status: |
None
Family Legal Status Report

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Parent Case: |
This application is a Continuation of application Ser. No. 08/945,882 filed on Nov. 13, 1997, now U.S. Pat. No. 5,980,866, which was filed as International Application PCT/JP97/00818, filed Mar. 14, 1997.

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Designated Country: |
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE AU CA EP JP KR US

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Family: |
Show 15 known family members

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First Claim:
Show all 10 claims |
What is claimed is:
1. An adhesive for tissue comprising a fibrinogen solution and a thrombin solution which solutions are separated from each other, said adhesive being to be mixed and sprayed together with a sterile gas for the adhesion or closing of living tissue of a human being or animal, wherein the volume ratio of the fibrinogen solution to the thrombin solution is about 2:1 to 10:1.

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Background / Summary: |
Show background / summary

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Drawing Descriptions: |
Show drawing descriptions

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Description: |
Show description

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Forward References: |
Show 2 U.S. patent(s) that reference this one

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Foreign References: |
Buy PDF |
Publication |
Date |
IPC Code |
Assignee |
Title |
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JP55110556
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1980-08 |
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JP58038217
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1983-03 |
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JP61293443
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1986-12 |
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JP02000114
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1990-01 |
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JP05038216
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1993-03 |
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WO9407420
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1994-04 |
A61B 17/00
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FUKUNAGA, Nobuto
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APPLICATOR FOR TISSUE ADHESIVE |

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Other Abstract Info: |
CHEMABS 127(16)225341C
DERABS C1997-489224

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Other References: |
Kiso to Rinsho (Basic and Clinical Report), vol. 20, No. 4, pp. 2399-2405, Mar. 1986.
Hiroshi Kaetsu et al., The Clinical Report, vol. 23, No. 10, pp. 3735-3743, "Studies on the Optimal Compounding Ratio of Fibrin Adhesive", Jul. 1989.

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