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Title: US7310555: Regulation of excitable tissue control of the heart based on physiological input
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Country: US United States of America

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15 pages

 
Inventor: Ben-Haim, Shlomo; Haifa, Israel
Darvish, Nissim; Haifa, Israel
Shemer, Itzhak; Haifa, Israel
Snir, Yehuda; Yokneam Illit, Israel

Assignee: Impulse Dynamics N.V., Curacao, Albania
Impulse Dynamics N.V., Curacao, Netherlands Antilles
other patents from IMPULSE DYNAMICS N.V. (776007) (approx. 33)
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Published / Filed: 2007-12-18 / 2004-03-10

Application Number: US2004000800169

IPC Code: Advanced: A61N 1/362; A61N 1/365;
Core: more...

ECLA Code: A61N1/362; A61N1/362C; A61N1/365C; K61N1/365B6;

U.S. Class: 607/009;

Field of Search: 607/009,19-20

Priority Number:
1998-11-16  IL1998000127092

Abstract:     A method and apparatus ( 30 ) for modifying contractility of the heart of a patient. The method includes receiving signals from a sensor ( 22, 23, 46 ) coupled to the body of the patient indicative of physiological activity. The signals are analyzed to derive a measure of the physiological activity, and excitable tissue control (ETC) stimulation is applied to the heart ( 20 ) so as to enhance contractility of the heart muscle responsive to the measure.

Attorney, Agent or Firm: Wolf, Block, Schorr & Solis-Cohen LLP ; Dippert, William H. ;

Primary / Asst. Examiners: Layno, Carl;

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Related Applications:
Application Number Filed Patent Pub. Date  Title
US2001000831100     2004-04-20  Regulation of excitable tissue control of the heart based on physiological input


       
Parent Case: CROSS-REFERENCE TO RELATED APPLICATIONS
    This application is a continuation patent application of U.S. patent application Ser. No. 09/831,100, filed Sep. 10, 2001 (now U.S. Pat. No. 6,725,093), which is the U.S. National Stage application of PCT Patent Application No. PCT/IL99/00594, filed Nov. 4, 1999, which claims priority from (a) U.S. Provisional Patent Application Ser. No. 60/107,479, filed Nov. 6, 1998, and (b) Israel Patent Application No. 127,092, filed Nov. 16, 1998, each of which is incorporated herein by reference.

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First Claim:
Show all 18 claims
    1. A method for modifying contractility of the heart of a patient, comprising:

receiving signals from a sensor coupled to the body of the patient indicative of physiological activity;

analyzing the signals to derive a measure of the physiological activity; and

applying excitable tissue control (ETC) stimulation to the heart so as to enhance contractility of the heart muscle responsive to the measure,

wherein analyzing the signals comprises assessing heart rate variability of the patient, and wherein applying the ETC stimulation comprises applying the ETC stimulation responsive to the heart rate variability.



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U.S. References: Go to Result Set: All U.S. references   |  No patents reference this one   |   Backward references (23)   |   Citation Link

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Patent  Pub.Date  Inventor Assignee   Title
Buy PDF- 10pp US4554922  1985-11 Prystowsky   Method of inhibiting cardiac arrhythmias
Buy PDF- 16pp US4884576  1989-12 Alt   Self adjusting rate responsive cardiac pacemaker and method
Buy PDF- 11pp US5018522  1991-05 Mehra  Medtronic, Inc. Ramped waveform non-invasive pacemaker
Buy PDF- 8pp US5083564  1992-01 Scherlag  Board of Regents of the University of Oklahoma Method for alleviating and diagnosing symptoms of heart block
Buy PDF- 13pp US5205284  1993-04 Freeman  Zoll Medical Corporation Method and apparatus for transcutaneous electrical cardiac pacing with background stimulation
Buy PDF- 13pp US5284491  1994-02 Suton et al.  Medtronic, Inc. Cardiac pacemaker with hysteresis behavior
Buy PDF- 17pp US5431688  1995-07 Freeman  ZMD Corporation Method and apparatus for transcutaneous electrical cardiac pacing
Buy PDF- 10pp US5447525  1995-09 Powell et al.  Medtronic, Inc. Pacemaker which adapts to minimize current drain and provide desired capture safety margin
Buy PDF- 21pp US5514162  1996-05 Bornzin et al.  Pacesetter, Inc. System and method for automatically determining the slope of a transfer function for a rate-responsive cardiac pacemaker
Buy PDF- 12pp US5620468  1997-04 Mongeon et al.  Medtronic, Inc. Method and apparatus for treatment of atrial fibrillation
Buy PDF- 21pp US5626622  1997-05 Cooper  Telectronics Pacing Systems, Inc. Dual sensor rate responsive pacemaker
Buy PDF- 15pp US5683429  1997-11 Mehra  Medtronic, Inc. Method and apparatus for cardiac pacing to prevent atrial fibrillation
Buy PDF- 26pp US5697953  1997-12 Kroll et al.  Angeion Corporation Implantable cardioverter defibrillator having a smaller displacement volume
Buy PDF- 9pp US5755740  1998-05 Nappholz   Pacemaker with automatic calibration of the response of multiple sensors
Buy PDF- 11pp US5792198  1998-08 Nappholz   Auto adaptation of RR interval in implantable pacemaker
Buy PDF- 26pp US5800464  1998-09 Kieval  Medtronic, Inc. System for providing hyperpolarization of cardiac to enhance cardiac function
Buy PDF- 14pp US5807234  1998-09 Bui et al.  Pacesetter, Inc. Myostimulator control using metabolic demand and muscle performance
Buy PDF- 11pp US5871506  1999-02 Mower   Augmentation of electrical conduction and contractility by biphasic cardiac pacing
Buy PDF- 17pp US6006134  1999-12 Hill et al.  Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
Buy PDF- 64pp US6233487  2001-05 Mika et al.  Impulse Dynamics N.V. Apparatus and method for setting the parameters of an alert window used for timing the delivery of ETC signals to a heart under varying cardiac conditions
Buy PDF- 14pp US6292693  2001-09 Darvish et al.  Impulse Dynamics N.V. Contractility enhancement using excitable tissue control and multi-site pacing
Buy PDF- 16pp US6725093  2004-04 Ben-Haim et al.  Impulse Dynamics N.V. Regulation of excitable tissue control of the heart based on physiological input
Buy PDF- 14pp US20040138710A1  2004-07 Shemer et al.   Signal delivery through the right ventricular septum
       
Foreign References:
Buy
PDF
Publication Date IPC Code Assignee   Title
Buy PDF- 35pp EP0503839 1992-09  A61B 8/06 TELECTRONICS N.V. Method and apparatus for chronically monitoring the hemodynamic state of a patient using doppler ultrasound. 
Buy PDF- 49pp WO9616696 1996-06  A61N 1/362 MEDTRONIC INC METHOD AND APPARATUS FOR AUTOMATIC PACING THRESHOLD DETERMINATION 
Buy PDF- 111pp WO9725098 1997-07  A61B BEN HAIM SHLOMO ELECTRICAL MUSCLE CONTROLLER 
Buy PDF- 55pp WO9810830 1998-03  A61N 1/36 BEN HAIM SHLOMO FENCING OF CARDIAC MUSCLES 
Buy PDF- 81pp WO9810831 1998-03  A61N 1/36 BEN HAIM SHLOMO CARDIAC OUTPUT CONTROLLER 
Buy PDF- 82pp WO9810832 1998-03  A61N 1/36 BEN HAIM SHLOMO CARDIAC OUTPUT ENHANCED PACEMAKER 
Buy PDF- 36pp WO9819719 1998-04  A61L 27/00 HAVEL, WILLIAM, J. MYOCARDIAL GRAFT CONSTRUCTS 
Buy PDF- 33pp WO9906105 1999-02  A61N 1/05 DESMOND, Noel, Gray IMPROVED HEART PACEMAKER 
Buy PDF- 24pp WO0001443 2000-01  A61B MOWER MORTON M AUGMENTATION OF ELECTRICAL CONDUCTION AND CONTRACTILITY BY BIPHASIC CARDIAC PACING 
Buy PDF- 44pp WO0004947 2000-02  A61N DARVISH NISSIM PACING WITH HEMODYNAMIC ENHANCEMENT 


Other References:
  • A.H. Foster et al., “Acute Hemodynamic Effects of Atrio-Biventricular Pacing In Humans”, 1995, The Society of Thoracic Surgeons vol. 59, pp. 294-299. (7 pages) Cited by 10 patents [ISI abstract]
  • S. Cazeau et al., “Multisite Pacing For End-Stage Heart Failure: Early Experience”, Pacing and Clinical Electrophysiology vol. 19, Nov. 1996, Part II, pp. 1748-1757. (10 pages) Cited by 11 patents [ISI abstract]
  • Yu et al., “Does Biventricular Pacing Provide Better Cardiac Function Than . . . ?” Abstract, Heart Failure Society Abstracts-on-Disk, Sep. 13-16, 1998 Boca Raton, Florida.
  • A. Auricchio et al., “Acute Pacing of the Left Ventricle is Associated with Largest . . . ”, Abstract, Heart Failure Society Abstracts-on-Disk, Sep. 13-16, 1998 Boca Raton, Florida.
  • C. Leclercq et al., “Comparative Effects of Permanent Viventricular Pacing In Class III & . . . ”, Pacing and Clinical Electrophysiology, Apr. 1998, vol. 21, No. 4, Part II, p. 911.
  • P.F. Bakker et al., “Beneficial Effects of Biventricular Pacing of Congestive Heart Failure”, PACE, vol. 17, Apr. 1994, Part II, one page.
  • P.F. Bakker et al., “Biventricular Pacing Improves Functional Capacity in Patients with End-Stage Congestive Heart Failure”, PACE, Apr. 1995, Part II, one page.
  • H. Antoni et al., “Polarization Effects of Sinusoidal 50 Hz Alternating Current on Membrane Potential of Mammalian Cardiac Fibres”, Pflugers Arch. 314, pp. 274-291, 1970. Cited by 23 patents
  • Guidant Product Catalogue, 2001, 2 pages. (http://www.guidant.com/glossary.htm.).


  • Continuity Data:
    Application Number Filed Notes

    US2004000800169 2004-03-10  is a related to the prior publication
         US20040215267A1 issued 2004-10-28  Regulation of excitable tissue control of the heart based on physiological input

    US2001000831100 2001-09-10  is a 371 of international
    WO1999IL0000594  1999-11-04   (pending)
         WO0027476A1 issued 2000-05-18   REGULATION OF EXCITABLE TISSUE CONTROL OF THE HEART BASED ON PHYSIOLOGICAL INPUT

    >US2004000800169<   is a continuation of
    US2001000831100  
         US6725093 issued 2004-04-20   Regulation of excitable tissue control of the heart based on physiological input

    >US2004000800169< 2004-03-10  is a continuation of
    US2001000831100  2001-09-10   (granted)
         US6725093 issued 2004-04-20   Regulation of excitable tissue control of the heart based on physiological input

    US2004000800169 2004-03-10  is a non-provisional of provisional
    US1998000107479P  1998-11-06


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