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Title: |
EP0012494A1:
A DNA transfer vector, a microorganism modified by said vector and the synthesis of a eucaryotic protein by the modified microorganism[German][French]
[ Derwent Title ]

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Country:
Kind: |
EP European Patent Office (EPO)
A1 APPLICATION PUBLISHED WITH SEARCH REPORT i
(See also:
EP0012494B1 )

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Inventor: |
Rutter, William J.;
Goodman, Howard M.;
Baxter, John D.;

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Assignee: |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
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Published / Filed: |
1980-06-25
/ 1979-08-13

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Application Number: |
EP1979000301630

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IPC Code: |
Advanced:
A61K 38/27;
C07K 14/005;
C07K 14/195;
C07K 14/575;
C07K 14/61;
C07K 14/62;
C07K 19/00;
C12N 1/20;
C12N 15/09;
C12P 19/34;
C12P 21/02;
C12R 1/19;
IPC-7:
C12N 15/00;
C12P 21/02;

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ECLA Code: |
C07K14/61; C07K14/62; M07K319/00; M07K319/75;

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Priority Number: |
| 1978-08-11 |
US1978000933035 |

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Abstract: |
A deoxyribonucleic acid (DNA) transfer vector is provided which comprises a nucleotide sequence coding for a eucaryotic protein joined to a procaryotic control fragment, the respective reading frames being in register, and the respective directions of transcription being the same. By connecting a eucaryotic gene to a gene for a protein normally compartmentalized or protected from intracellular degradation in some manner, the stability of a chimeric protein may by enhanced. A eucaryatic gene may be linked to a gene which has desirable genetic properties. In addition to the DNA transfer vector, the invention also provides a microorganism transformed by the transfer vector, a protein synthesised by such a microorganism, and a method of synthesising a protein.

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INPADOC Legal Status: |
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Designated Country: |
BE CH DE FR LU NL SE

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Family: |
Show 26 known family members

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