This invention relates to a pharmaceutical composition for treating gastrointestinal distress comprising an effective amount of an antidiarrheal composition, e.g. loperamide, and an antiflatulent effective amount of simethicone and methods of treating gastrointestinal distress comprising administering such pharmaceutical compositions.
+Field of the Invention This invention relates to a pharmaceutical composition for treating gastrointestinal distress comprising an effective amount of an antidiarrheal composition and an antiflatulent effective amount of simethicone and methods of its use.
+Background of the Invention +Summary of the Invention +Detailed Description of Preferred Embdoments of the Invention +Examples +Manufacturing Instructions +A. Simethicone Granulation +B. Loperamide Granulation +C. Compression +Manufacturing Instructions +A. Simethicone Granulation +B. Loperamide Granulation +C. Compression +Manufacturing Instructions +Example IV. Bismuth Subsalicylate 300 mg/Simethicone 80mg Emulsion/Suspension +Example V. Loperamide 2mg/Bismuth Subsalicylate 300 mg./Simethicone 80 mg. Emulsion/Suspension +Method of Treating Patients with Gastrointestinal Distress