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 Title: |
EP1015872A2:
APPARATUS AND METHOD FOR DETECTING AND IDENTIFYING INFECTIOUS AGENTS[German][French]
[ Derwent Title ]
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Country:
Kind: |
EP European Patent Office (EPO)
A2 APPLICATION PUBLISHED WITHOUT SEARCH REPORT i
(See also:
EP1015872B1, WO09826277 )
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| Inventor: |
BRYAN, Bruce, J.;
GAALEMA, Stephen;
MURPHY, Randall, B.;
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| Assignee: |
Prolume, Ltd.
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| Published / Filed: |
2000-07-05
/ 1997-12-12
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| Application Number: |
EP1997000954785
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| IPC Code: |
Advanced:
G01N 21/25;
G01N 21/76;
G01N 33/543;
Core:
more...
IPC-7:
A61F 2/02;
C01B 33/149;
C12Q 1/66;
G01N 21/76;
G01N 33/53;
G01N 33/58;
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| Priority Number: |
| 1996-12-12 |
US1996000033745P |
| 1997-02-11 |
US1997000037675P |
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| Abstract: |
Solid phase methods for the identification of an analyte in a biological medium, such as a body fluid, using bioluminescence are provided. A chip designed for performing the method and detecting the bioluminescence is also provided. Methods employing biomineralization for depositing silicon on a matrix support are also provided. A synthetic synapse is also provided.
[French]
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| Attorney, Agent or Firm: |
Baldock, Sharon Claire ;
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| INPADOC Legal Status: |
Show legal status actions
Family Legal Status Report
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| Designated Country: |
AL AT BE CH DE DK ES FI FR GB GR IE IT LI LT LU LV MC MK NL PT RO SE SI
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| Family: |
Show 23 known family members
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Description
Expand description |
[From equivalent
EP1015872B1]
+ RELATED APPLICATIONS
This application claims priority to U.S Provisional appplication Serial No. 60/037,675, filed February 11, 1997 and to U.S. Provisional application Serial No. 60/033,745, filed December 12, 1996.
+ FIELD OF INVENTION
+ BACKGROUND OF THE INVENTION
+ Bioluminescence
+ Chips, arrays and microelectronics
+ SUMMARY OF THE INVENTION
+ Brief Description of the Drawings
+ DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
+ TABLE OF CONTENTS
+ A. Definitions
+ B. Bioluminescence generating systems
+ 1. General description
+ a. Luciferases
+ b. Luciferins
+ c. Activators
+ d. Reactions
+ 2. Ctenophore and coelenterate systems
+ a. The aequorin system
+ (1) Aequorin and related photoproteins
+ (2) Luciferin
+ b. The Renilla system
+ Recombinant production of Renilla reniformis luciferase
+ 3. Crustacean, particularly Cyrpidina systems
+ a. Vargula luciferase
+ (1) Purification from Cypridina
+ (2) Preparation by Recombinant Methods
+ b. Vargula luciferin
+ c. Reaction
+ 4. Insect bioluminescence generating systems including firefly, click beetle, and other insect systems
+ a. Luciferase
+ b. Luciferin
+ c. Reaction
+ 5. Bacterial systems
+ a. Luciferases
+ b. Luciferins
+ c. Reactions
+ 6. Other systems
+ a. Dinoflagellate bioluminescence generating systems
+ b. Systems from molluscs, such as Latia and Pholas
+ c. Earthworms and other annelids
+ d. Glow worms
+ e. Marine polycheate worm systems
+ f. South American railway beetle
+ g. Fish
+ 7. Fluorescent Proteins
+ a. Green and blue fluorescent proteins
+ b. Phycobiliproteins
+ C. Design, fabrication, and use of chips
+ 1. Nonself-addressable chips
+ 2. Self addressable chips
+ a. Matrix materials
+ b. Fabrication Procedures
+ i. Microlithography
+ ii. Micromachining
+ c. Self-addressing of chips
+ 3. Attachment of biological molecules to the surface of chips
+ a. Derivatization of silica substrates
+ b. Attachment of biological molecules
+ D. Formation of luciferase conjugates
+ 1. Linkers
+ 2. Luciferase fusion proteins
+ 3. Nucleic acid and peptide nucleic acid conjugates
+ E. Radiolaria and diatoms for depositing silica on matrices
+ F. Methods of use
+ 1. Immunoassays
+ 2. Nucleic acid hybridization assays
+ 3. Detection of antibiotic sensitivity
+ 4. Synthetic synapse
+ SEQUENCE LISTING
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| Other Abstract Info: |
CHEMABS 129(06)065194T
DERABS C1998-348686
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