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 Title: |
US5470701:
Method for determining favorable prognosis in an HIV positive subject using HLA-DR+ /CD38- CD8bright cells
[ Derwent Title ]
>> View Certificate of Correction for this publication
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| Country: |
US United States of America
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| Inventor: |
Giorgi, Janis V.; Woodland Hills, CA
Hultin, Lance; West Hills, CA
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| Assignee: |
The Regents of the University of California, Los Angeles, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
1995-11-28
/ 1993-02-24
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| Application Number: |
US1993000022971
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| IPC Code: |
Advanced:
G01N 33/50;
G01N 33/569;
Core:
more...
IPC-7:
G01N 33/569;
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| ECLA Code: |
G01N33/50D4; G01N33/569K2;
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| U.S. Class: |
Current:
435/005;
435/007.24;
Original:
435/005;
435/007.24;
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| Field of Search: |
435/005,7.24,475
422/82.08
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| Government Interest: |
This invention was made with support under Grant Numbers AI-72631 and AI-72656 from the National Institute of Health, U.S. Department of Health and Human Resources. Accordingly, the U.S. Government may have certain rights in the invention.
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| Priority Number: |
| 1993-02-24 |
US1993000022971 |
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| Abstract: |
The subject invention involves an approach to determining the favorable prognosis of a subject infected with HIV. Specifically, the discovery involves the importance of the elevated presence of MHC class II antigen+ /CD38- /CD8bright cells for the prognosis of favorable outcome in HIV-infected subjects. In one example the MHC class II antigen may be HLA-DR.
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| Attorney, Agent or Firm: |
Merchant, Gould, Smith, Edell, Welter & Schmidt ;
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| Primary / Asst. Examiners: |
Saunders, David;
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| Maintenance Status: |
CC Certificate of Correction issued
View Certificate of Correction
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| INPADOC Legal Status: |
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Family Legal Status Report
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| Designated Country: |
AU CA EP JP
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| Family: |
Show 3 known family members
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First Claim:
Show all 29 claims |
What is claimed is:
1. A method for determining a favorable prognosis in an HIV positive subject which comprises quantitatively detecting an elevated level of HLA-DR+ /CD38- /CD8bright cells thereby determining a favorable prognosis in the HIV positive subject.
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| Background / Summary: |
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| Drawing Descriptions: |
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| Description: |
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| Forward References: |
Show 1 U.S. patent(s) that reference this one
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| Foreign References: |
None
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| Other Abstract Info: |
DERABS C94-294473
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| Other References: |
B. Autran et al in Janossy et al (Eds.) Immunodeficiency in HIV Infection and AIDS, Basel, Karger, 1992, pp. 171-184.
J. V. Giorgi et al, Clinical Immunology and Immunopathology, 52, 10-18, 1989.
(9 pages)
Cited by 4 patents
H-N Ho et al, Journal of Immunology, 150, 3070-3079, 1993.
(10 pages)
[ISI abstract]
L. Kestens et al. AIDS, 6, 793-797, 1993.
J. B. Peter, Use and Interpretation of Tests in Clinical Immunology, Interstate Press, Omaha, 1990, p. 23.
H. E. Prince et al, Diagnostic and Clinical Immunology, 5, 188-193, 1987.
(6 pages)
H. E. Prince et al, Journal of Acquired Immune Deficiency Syndromes, 4, 1227-1232, 1991.
(6 pages)
Cited by 2 patents
[ISI abstract]
M. J. Yagi et al, Journal of Infectious Diseases, 164, 183-188, 1991.
(6 pages)
[ISI abstract]
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