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 Title: |
US5643787:
Adenocarcinoma cell basement membrane composition
[ Derwent Title ]
>> View Certificate of Correction for this publication
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| Country: |
US United States of America
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| Inventor: |
Barsky, Sanford H.; Los Angeles, CA
Sternlicht, Mark; Los Angeles, CA
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
1997-07-01
/ 1995-01-31
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| Application Number: |
US1995000381384
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| IPC Code: |
Advanced:
C12N 5/06;
C12N 5/16;
G01N 33/50;
Core:
more...
IPC-7:
C12N 5/00;
C12N 5/02;
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| ECLA Code: |
C12N5/06B30;
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| U.S. Class: |
Current:
435/371;
435/366;
435/373;
435/378;
435/383;
435/391;
435/395;
Original:
435/371;
435/378;
435/373;
435/395;
435/383;
435/391;
435/366;
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| Field of Search: |
435/172.3,240.1,371,240.2,373,240.21,240.25,391
424/93.1
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| Priority Number: |
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| Abstract: |
Methods and compositions are provided for the culture of human primary carcinomas and in situ carcinomas. Feeder layers derived from a human parotid basal cell carcinoma, having the HMS-1 phenotype, are able to support the growth of the primary carcinomas, and allow for spheroid formation. Invasion inhibiting factors active against human tumors, derived from HMS-1, are also provided.
Human basement membrane and extracellular matrix is provided, produced by a tumorigenic cell line, where the basement membrane and extracellular matrix can be used for the growth of a variety of cells, in culture and in vivo. Other related cell lines are provided, which can serve to evaluate in vivo the response of tumorigenic cells to various agents, including basement membrane and extracellular matrix. The basement membrane and extracellular matrix finds use in allowing the growth of cells in culture and in vivo, particularly cells which are otherwise refractory to xenografting.
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| Attorney, Agent or Firm: |
Flehr Hohbach Test Albritton & Herbert LLP ;
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| Primary / Asst. Examiners: |
Crouch, Deborah;
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| Maintenance Status: |
E1 Expired Check current status
CC Certificate of Correction issued
View Certificate of Correction
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| INPADOC Legal Status: |
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