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Title: US5658757: Cloned leptospira outer membrane protein
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Country: US United States of America

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19 pages

 
Inventor: Haake, David A.; Culver City, CA
Blanco, David R.; Beverly Hills, CA
Champion, Cheryl I.; Culver City, CA
Lovett, Michael A.; Los Angeles, CA
Miller, James N.; Northridge, CA

Assignee: The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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Published / Filed: 1997-08-19 / 1994-12-20

Application Number: US1994000362739

IPC Code: Advanced: C07K 14/20; A61K 39/00;
Core: C07K 14/195; more...
IPC-7: C07H 19/00; C12D 21/06; C12N 5/00; C12N 15/00;

ECLA Code: C07K14/20;

U.S. Class: Current: 435/069.1; 435/252.3; 435/252.33; 435/320.1; 435/325; 435/419; 435/810; 536/023.7; 536/024.32;
Original: 435/069.1; 435/252.3; 435/252.33; 435/320.1; 435/810; 435/325; 435/419; 536/023.7; 536/024.32;

Field of Search: 536/23.7,24.32 435/69.1,240.2,252.3,252.33,320.1,810

Government Interest:     This invention was made with government support under Grant Number AI-21352 by the National Institute of Health. The government has certain rights in the invention.

Priority Number:
1994-12-20  US1994000362739
1993-03-31  US1993000040747

Abstract: An antigenic preparation is provided which contains a 31 Kd outer membrane protein from Leptospira which can be used immunologically as a vaccine for leptospirosis caused by this organism.

Attorney, Agent or Firm: Fish & Richardson, P.C. ;

Primary / Asst. Examiners: Jagannathan, Vasu S.; Romeo, David

Maintenance Status: CC Certificate of Correction issued
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Related Applications: Go to Result Set: 3 patent(s) that list this one as related
Application Number Filed Patent Pub. Date  Title
US1993000040747 1993-03-31       


       
Parent Case:     This is a continuation of application Ser. No. 08/040,747 filed on Mar. 31, 1993, now abandoned.

Family: Show 4 known family members

First Claim:
Show all 14 claims
We claim:     1. An isolated polynucleotide sequence which encodes the amino acid of SEQ ID NO:2.

Background / Summary: Show background / summary

Drawing Descriptions: Show drawing descriptions

Description: Show description

Forward References: Show 6 U.S. patent(s) that reference this one

       
U.S. References: Go to Result Set: All U.S. references   |  Forward references (6)   |   Backward references (5)   |   Citation Link

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PDF
Patent  Pub.Date  Inventor Assignee   Title
Buy PDF- 11pp US5091301  1992-02 Zuerner  The Unites States of America as represented by the Secretary of Agriculture Diagnostic and epidemiological nucleic acid probe for bovine leptospirosis
Buy PDF- 22pp US5397698  1995-03 Goodman et al.  Syntex (U.S.A.) Inc. Amplification method for polynucleotide detection assays
Buy PDF- 23pp US5401631  1995-03 Lane et al.  Amoco Corporation Universal eubacteria nucleic acid probes and assay methods
Buy PDF- 13pp US5466577  1995-11 Weisburg  Amoco Corporation Nucleic acid probes for the detection of Lyme disease spirochetes
Buy PDF- 14pp US5516641  1996-05 Ullman et al.  Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
       
Foreign References: None

Other Abstract Info: CHEMABS 127(15)202796R CHEMABS 127(15)202796R DERABS C1997-424233 DERABS C1997-424233

Other References:
  • Blanchard-Channell et al. "Characterization of Borrelia coriaceae Antigens with Monoclonal Antibodies", Inf. Immun.59)8):2790-2748 (Aug. 1991). (9 pages) Cited by 4 patents [ISI abstract]
  • Allan et al. "Molecular Cloning of the Major Outer Membrane Protein of Chlamydia trachomatis", Inf. Immun.45(3):637-641 (Sep. 1984). (5 pages) Cited by 8 patents
  • Haake et al. "Changes in the Surface of Leptospira interrogansSerovar Grippotyphosa During In Vitro Cultivation", Inf. Immun.59(3):1131-1140 (Mar. 1991). (10 pages) Cited by 6 patents [ISI abstract]
  • Van Eys et al. "DNA Hybridization . . . Leptospira. . ." J. Gen. Microbiol. 134:567-574 (Mar. 1988). (8 pages) Cited by 5 patents
  • Doherty et al. "Expression of two conserved leptospiral antigens in E. coli" J. Med. Microbiol. 28(2):143-150 (1989), in Biol. Abstr.87(11):AB-477, #115457 (Jun. 1989). (7 pages) Cited by 4 patents
  • Richaud et al. "Cloning of Genes for Amino Acid Biosynthesis from Leptospira . . . ", J. Gen. Microbiol.136:651-656
  • (Apr. 1990).
  • Baril et al. "Sizing of the Leptospira genome . . . " Fems Microbiol. Lett.71: 95-100 (Sep. 1990). (5 pages) Cited by 4 patents
  • Penn et al, "Genetic Approaches to Cell Biology and Metabolism of Spirochetes ", Res. Microbiol. 143: 605-613 (Jul./Aug. 1992). (9 pages) Cited by 4 patents [ISI abstract]
  • Yasuda et al. "Deoxyribonucleic Acid Relatedness Between Serogroups and Serovavs in the Family Leptospiraceae. . ." Int. J. Sys. Bact. 37(4):407-415 (Oct. 1987). (9 pages) Cited by 6 patents
  • Zuerner et al. "Characterization of Outer Membrane and Secreted Proteins of Leptospira . . ." Microbial Pathogen. 10:311-322 (Apr. 1991). (12 pages) Cited by 9 patents [ISI abstract]


  • Continuity Data:
    Application Number Filed Notes

    US2002000322391 2002-12-17  is a continuation of
    US1997000914350  1997-08-19   (pending) [presumed granted]
         US6685945 issued 2004-02-03   Cloned Leptospira outer membrane protein

    US1997000914350 1997-08-19  is a division of
    >US1994000362739<  1994-12-20   (granted)
         US5658757 issued 1997-08-19   Cloned leptospira outer membrane protein

    >US1994000362739< 1994-12-20  is a continuation of
    US1993000040747  1993-03-31   (abandoned)


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