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Title: US5705626: Cloned glutamic acid decarboxylase nucleic acids
[ Derwent Title ]

Country: US United States of America

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32 pages

 
Inventor: Tobin, Allan J.; Los Angeles, CA
Erlander, Mark G.; Tarzana, CA
Kaufman, Daniel L.; Santa Monica, CA

Assignee: The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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Published / Filed: 1998-01-06 / 1995-06-07

Application Number: US1995000485718
IPC Code: Advanced: C12N 9/88; A61K 38/00;
Core: more...
IPC-7: C12N 15/12; C12N 15/60;

ECLA Code: C12N9/88; K61K38/00; M12N203/00; M12N207/00; S01N800/04A; S01N800/24;

U.S. Class: Current: 536/023.5; 435/232; 536/023.2;
Original: 536/023.5; 536/023.2; 435/232;

Field of Search: 536/23.5,23.2 435/232

Government Interest:     The present invention was supported by Grant NS22256 from the National Institutes of Health. The United States Government has certain rights in this invention.

Priority Number:
1995-06-07  US1995000485718
1993-10-13  US1993000135849
1991-06-18  US1991000716909
1990-09-21  US1990000586536

Abstract:     The invention is directed to isolated polypeptides useful in ameliorating autoimmune disease.

Attorney, Agent or Firm: Rowland, Bertram I. ;

Primary / Asst. Examiners: Hendricks, Keith D.;

INPADOC Legal Status: None          Buy Now: Family Legal Status Report

       
Related Applications:
Application Number Filed Patent Pub. Date  Title
US1993000135849 1993-10-13    1995-12-12  Cloned glutamic acid decarboxylase peptides
US1991000716909 1991-06-18       
US1990000586536 1990-09-21       


       
Parent Case:     This is division of application Ser. No. 08/135,849 filed Oct. 13, 1993 now U.S. Pat. No. 5,475,086, a continuation of Ser. No. 07/716,909 filed Jun. 18, 1991, now abandoned, which is a continuation-in-part of 07/586,536 filed Sep. 21, 1990.

Designated Country: BE CH FR GB IT LI LU MC NL PT SE  NO 

Family: Show 67 known family members
First Claim:
Show all 6 claims		 We claim:     1. An isolated polynucleotide sequence encoding the polypeptide of the amino acid sequence:
  • X-Pro-Glu-Val-Lys-Y-Lys-Z
  • wherein X is an amino acid sequence selected from one to ten amino acids or omitted; Y is Glu; and Z is an amino acid sequence selected from one to eight amino acids or omitted wherein the polypeptide stimulates in vitro proliferation of human T lymphocytes.
    •


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Forward References: Show 4 U.S. patent(s) that reference this one

       
U.S. References: Go to Result Set: All U.S. references   |  Forward references (4)   |   Backward references (0)   |   Citation Link

       
Foreign References: None

Other Abstract Info: CHEMABS 117(23)227775Q CHEMABS 118(23)225673B CHEMABS 127(23)315578Q DERABS C1992-150489 DERABS C1992-425701 DERABS C2000-095930 DERABS C2000-500251

Other References:
  • Gerling et al., Effect of Coxsackie virus B4 infection in mice on expression of 64,000-Mr Autoantigen . . . , pp. 1419-1425, Oct. 1988. (7 pages) Cited by 6 patents
  • Dryberg, T. Molecular Mimicry and Diabetes, pp. 117-125, 1989.
  • Schwimmbeck et al., Molecular Mimicry and Myashenia Gravis, pp. 1174-1180, Oct. 1989. (7 pages) Cited by 7 patents
  • Todd, et al., A molecular basis for genetic susceptibility to insulin-dependent diabetes . . . , pp. 129-134 May 1988. (6 pages) Cited by 7 patents
  • Wraith et al., Antigen recognition in autoimmune encephalomyelitis . . . , pp. 247-255, Oct. 1989. (9 pages) Cited by 56 patents
  • Chang et al., J. Neurosci., 8(6):2123-2130, Jun. 1988. (8 pages) Cited by 14 patents
  • Julien et al., J. Neurochem., 54(2):703-705, 1990. (3 pages) Cited by 16 patents
  • Julien et al., Neurosci. Lett., vol. 73, pp. 173-180, 1987. (8 pages) Cited by 9 patents
  • Baekkeskov et al., Diabetes, vol. 38, pp. 1133-1141, Sep. 1989. (9 pages) Cited by 9 patents
  • Legay et al., J. Neurochem., 48(4): 1022-1026, 1987. (5 pages) Cited by 9 patents
  • Geysen et al., PNAS, vol. 81, pp. 3998-4002, Jul. 1984.


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