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Title: US5794629: Method for treating ischemic brain stroke
[ Derwent Title ]


Country: US United States of America

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11 pages

 
Inventor: Frazee, John G.; Toluca Lake, CA

Assignee: The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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Published / Filed: 1998-08-18 / 1996-11-27

Application Number: US1996000757303

IPC Code: Advanced: A61M 1/36;
Core: more...
IPC-7: A61B 19/00;

ECLA Code: A61M1/36C;

U.S. Class: Current: 128/898; 604/509;
Original: 128/898; 604/049;

Field of Search: 128/898 600/016,18 604/053

Priority Number:
1996-11-27  US1996000757303

Abstract: A method for treating a patient sustaining an acute ischemic stroke in the brain. The brain has a blood circulatory system including a torcular Herophili and first and second transverse venous sinuses adjoining the torcular Herophili. The method comprises at least partially occluding the first and second transverse venous sinuses in first and second locations, respectively, adjacent to the torcular Herophili to partially obstruct venous blood drainage while permitting some antegrade venous blood flow from at least one of the transverse venous sinuses. A flow of the patient's arterial blood is introduced into at least one of the transverse venous sinuses to provide a substantially continuous retrograde blood flow into the venous side of the brain of the patient to overcome the lack of arterial blood flow for a period of time until the patient exhibits at least some resolution of ischemic brain symptoms.

Attorney, Agent or Firm: Myers, Richard L. ;

Primary / Asst. Examiners: Millin, Vincent; O'Hara, Kelly

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Designated Country: CA EP JP US 

Family: Show 3 known family members

First Claim:
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What is claimed:     1. A method for treating a patient sustaining an acute ischemic stroke in the brain, the brain having a blood circulatory system including a torcular Herophili and first and second transverse venous sinuses adjoining the torcular Herophili, the method comprising at least partially occluding the first and second transverse venous sinuses in first and second locations respectively adjacent to the torcular Herophili to partially obstruct venous blood drainage while controlling the degree of said at least partially occluding the first and second transverse venous sinuses to permit some antegrade venous blood flow from at least one of said transverse venous sinuses and introducing a flow of the patient's arterial blood into at least one of said transverse venous sinuses distal to said locations to provide a substantially continuous retrograde blood flow into the venous side of the brain of the patient to overcome the lack of arterial blood flow for a period of time until the patient exhibits at least some resolution of ischemic brain symptoms.

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Forward References: Show 19 U.S. patent(s) that reference this one

       
U.S. References: Go to Result Set: All U.S. references   |  Forward references (19)   |   Backward references (5)   |   Citation Link

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PDF
Patent  Pub.Date  Inventor Assignee   Title
Buy PDF- 8pp US4850969  1989-07 Jackson  Retroperfusion Systems, Inc. Retroperfusion catheter and tip construction for use therewith
Buy PDF- 14pp US4865581  1989-09 Lundquist et al.  Retroperfusion Systems, Inc. Retroperfusion control apparatus, system and method
Buy PDF- 11pp US4917667  1990-04 Jackson  Retroperfusion Systems, Inc. Retroperfusion balloon catheter and method
Buy PDF- 4pp US4927412  1990-05 Menasche  Retroperfusion Systems, Inc. Coronary sinus catheter
Buy PDF- 30pp US5011468  1991-04 Lundquist et al.  Retroperfusion Systems, Inc. Retroperfusion and retroinfusion control apparatus, system and method
       
Foreign References: None

Other Abstract Info: DERABS G98-322421

Other References:
  • Frazee et al. "Ischemic Brain Rescue By Transvenous Perfusion in Baboons With Venous Sinus Occlusion," Stroke, vol. 21, No. 1, Jan. 1990.
  • Kar et al. "Reversal of cerebral ischemia by transvenous retroperfusion of arterial blood." Circulation 80(4 Suppl. 2): II405, 1989.
  • Frazee et al. "Ischemic brain rescue by transvenous perfusion in baboons with venous sinus occlusion." Stroke 21:87-93, 1990. (7 pages)
  • Kardos. Neuroperfusion, Inc., Summary Federal Report on "Cerebral Retroperfusion Device for Ischemic Stroke" 1993.
  • Alexander et al. "Transvenous Retroperfusion in an experimental model of cerebral ischemia improves somatosensory evoked potentials and cerebral perfusion." Stroke 25(3):753, 1994. (1 pages) [ISI abstract]


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