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Title: US5804201: Immunomodulatory peptides of vespid antigen 5
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Country: US United States of America

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59 pages

 
Inventor: King, Te Piao; New York, NY

Assignee: The Rockefeller University, New York, NY
other patents from ROCKEFELLER UNIVERSITY (479685) (approx. 357)
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Published / Filed: 1998-09-08 / 1996-03-11

Application Number: US1996000614935
IPC Code: Advanced: A61K 31/00; A61K 38/00; A61K 39/35; A61P 37/00; A61P 37/08; C07K 7/08; C07K 14/435;
Core: C07K 7/00; more...
IPC-7: A61K 38/04; A61K 39/35;

ECLA Code: C07K14/435A4B;

U.S. Class: Current: 424/275.1; 424/184.1; 424/185.1; 435/069.1; 530/300; 530/806; 530/858; 536/023.2; 536/023.5;
Original: 424/275.1; 424/184.1; 424/185.1; 435/069.1; 530/300; 530/806; 530/858; 536/023.2; 536/023.5;

Field of Search: 435/69.1 530/300,806-856 536/23.2,23.5 424/184.1,185.1,275.1

Government Interest:     The research leading to the present invention was supported by United States Public Health Service Grant No. AI-17021. The government may have certain rights in the invention.

Priority Number:
1996-03-11  US1996000614935

Abstract: The present invention is directed to immunogenic peptides from vespid antigen 5. These immunogenic peptides can be used in immunotherapy for vespid venom allergic individuals. The present invention is thus directed to T cell epitopes of vespid antigen 5 that can anergize T cell responses in sensitive individuals.

Attorney, Agent or Firm: Klauber & Jackson ;

Primary / Asst. Examiners: Knodf, Marian C.; Zeman, Mary K.
Maintenance Status: CC Certificate of Correction issued
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Designated Country: AL AM AP AZ BA BB BG BR BY CN CU CZ EE GE GH HU IL IS KG KP KR KZ LC  AT BE CH DE DK ES FI FR GB GR IE IT LI 

Family: Show 8 known family members
First Claim:
Show all 12 claims		 What is claimed is:     1. A peptide characterized by the following properties:
  • a. having between 8 and 35 amino acid residues of vespid venom antigen 5; and
  • b. said peptide is antigenic for T cell proliferation in a mouse immunized with a vespid venom antigen 5, which mouse is a strain selected from the group consisting of BALB/c, ASW/Sn, C3H/He, and P/J.
    •


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Forward References: Show 1 U.S. patent(s) that reference this one

       
U.S. References: Go to Result Set: All U.S. references   |  Forward references (1)   |   Backward references (0)   |   Citation Link

       
Foreign References: None

Other Abstract Info: CHEMABS 127(21)292054Z DERABS C1997-470817

Other References:
  • King et al. Jan. 1990 Protein Seq. Data Anal. 3: 263-266.
  • Hoffman et al. Jan. 1993 J Allergy Clin. Immunol. 92: 707-716. (10 pages) [ISI abstract]
  • Hoffman, "Hymenoptia Venom Proteins" in National Toxins, R.B. Singh (ed.), Plenum Publishing 6 (1996).
  • King et al., J. Allergy Clin. Immunol.98:588-600 (1996). (13 pages) Cited by 7 patents [ISI abstract]
  • Muller et al., J. Allergy Clin. Immunol. 97:426 (1996).
  • Forster et al. (1995) J. Allergy Clin. Immunol. 95:1229-35. (7 pages) Cited by 4 patents [ISI abstract]
  • King et al., J. Immunol., 154:577 (1995). (8 pages) Cited by 6 patents [ISI abstract]
  • Muller et al., J. Allergy Clin. Immunol. 96:395-402 (1995). (8 pages) Cited by 2 patents [ISI abstract]
  • Norman et al., J. Allergy Clin. Immunol. 95:259 (1995). (1 pages) Cited by 2 patents [ISI abstract]
  • Briner et al., Proc. Natl. Acad. Sci. U.S.A., 90:7608-12 (1993). (5 pages) Cited by 16 patents [ISI abstract]
  • Hoyne et al., J. Exp. Med., 178:1783-1788 (1993). (6 pages) Cited by 6 patents [ISI abstract]
  • T.P. King, in "Bronchial Asthma," edited by E.B. Weiss and M. Stein, Little Brown, Boston, pp. 43-49 (1993).
  • King et al., J. Allergy Clin. Immunol., 91:283 (1993). (1 pages) Cited by 4 patents [ISI abstract]
  • Lu et al., J. Immunol. 150:2823 (1993). (8 pages) Cited by 10 patents [ISI abstract]
  • P.S. Norman, Current Op. Immunol., 5:968 (1993). (6 pages) Cited by 3 patents [ISI abstract]
  • O'Hehir et al., Eruop. J. Clin. Invest., 23:763 (1993). (10 pages) Cited by 2 patents [ISI abstract]
  • Mizuku et al., Mammalian Genome, 3:274-280 (1992).
  • Ales-Martinez, et al., Immunol. Today, 12:201 (1991). (5 pages) Cited by 6 patents [ISI abstract]
  • O'Hehir et al., Ann. Rev. Immunol., 9:67 (1991). (29 pages) Cited by 11 patents [ISI abstract]
  • Fang et al., Proc. Natl. Acad. Sci., USA, 85:895-899 (1988). (5 pages) Cited by 13 patents
  • King, J. Allergy Clin. Immunol., 79:113 (1987). (8 pages) Cited by 6 patents
  • Hoffman, J. Allergy and Clin. Immunol., 75:611 (1985). (3 pages) Cited by 6 patents
  • King, et al., J. Allergy and Clin. Immunol., 75:621 (1985). (8 pages) Cited by 8 patents


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