 |
|
|
|
|
|
 Title: |
US5824645:
Method of treating inflammation
[ Derwent Title ]
|
| Country: |
US United States of America
|
| |
| Inventor: |
Justice, Alan; Sunnyvale, CA
Singh, Tejinder; Palo Alto, CA
Gohil, Kishor Chandra; Richmond, CA
Valentino, Karen L.; San Carlos, CA
Miljanich, George P.; Redwood City, CA
|
| Assignee: |
Neurex Corporation, Menlo Park, CA
other patents from NEUREX CORPORATION (397535) (approx. 15)
News, Profiles, Stocks and More about this company
|
| Published / Filed: |
1998-10-20
/ 1996-11-01
|
| Application Number: |
US1996000742774
|
| IPC Code: |
Advanced:
A61K 38/17;
C07K 14/435;
G01N 33/94;
A61K 38/00;
Core:
more...
IPC-7:
A61K 38/00;
A61K 38/02;
C07K 5/00;
C07K 7/00;
|
| ECLA Code: |
A61K38/17; C07K14/435; G01N33/94P;
|
| U.S. Class: |
Current:
514/012;
514/013;
514/014;
514/015;
514/021;
530/321;
530/324;
530/325;
530/326;
Original:
514/012;
514/021;
514/013;
514/014;
514/015;
530/321;
530/324;
530/325;
530/326;
|
| Field of Search: |
514/012,13,14,15,21
530/324,325,326,327
|
| Priority Number: |
|
| Abstract: |
A method of producing analgesia in nociceptive and neuropathic pain is disclosed. The method includes administering to a subject an omega conopeptide which is characterized by its ability to (a) inhibit electrically stimulated contraction of the guinea pig ileum, and (b) bind selectively to omega conopeptide MVIIA binding sites present in neuronal tissue. Also disclosed are novel omega conotoxin peptides effective in producing analgesia.
|
| Attorney, Agent or Firm: |
Stratford, Carol A. ;
Dehlinger, Peter J. ;
|
| Primary / Asst. Examiners: |
Davenport, Avis M.;
|
| INPADOC Legal Status: |
Show legal status actions
Family Legal Status Report
|
|
|
|
|
|
|
| Parent Case: |
This is a continuation of application Ser. No. 08/675,354, filed Jul. 3, 1996 now pending, which is a continuation of allowed application Ser. No. 08/049,794, filed Apr. 15, 1993 now U.S. Pat. No. 5,587,454, which is a continuation-in-part of application Ser. No. 07/814,759, filed Dec. 30, 1991, now abandoned.
|
| Designated Country: |
BE CH DK ES FR GB GR IE IT LI LU MC NL PT SE CA HU JP KR NO RU
|
| Family: |
Show 18 known family members
|
First Claim:
Show all 9 claims |
It is claimed:
1. A method of treating inflammation in a subject, in need of said treatment comprising
- administering to the subject a pharmacologically effective dose of an omega-conopeptide effective to (i) block voltage-gated calcium channels, (ii) bind with high affinity to an omega conopeptide binding site, and (iii) inhibit neurotransmitter release from nervous tissue.
|
| Background / Summary: |
Show background / summary
|
| Drawing Descriptions: |
Show drawing descriptions
|
| Description: |
Show description
|
| Forward References: |
Show 3 U.S. patent(s) that reference this one
|
|
