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 Title: |
US5856551:
Macromolecular structure for boron neutron-capture therapy
[ Derwent Title ]
>> View Certificate of Correction for this publication
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| Country: |
US United States of America
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| Inventor: |
Kane, Robert R.; Los Angeles, CA
Hawthorne, M. Frederick; Encino, CA
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
1999-01-05
/ 1997-02-27
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| Application Number: |
US1997000810333
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| IPC Code: |
Advanced:
A61K 41/00;
C07F 9/6596;
Core:
C07F 9/00;
more...
IPC-7:
C07F 9/09;
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| ECLA Code: |
A61K41/00Z4; C07F9/6596;
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| U.S. Class: |
Current:
558/072;
Original:
558/072;
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| Field of Search: |
558/072
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| Priority Number: |
| 1997-02-27 |
US1997000810333 |
| 1995-01-11 |
US1995000371563 |
| 1993-03-12 |
US1993000030920 |
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| Abstract: |
A general synthetic method has been developed for the rapid and efficient production of a variety of boron-rich macromolecules suitable for conjugation with of inclusion in receptor-mediated delivery systems as well as other delivery systems. Preparation techniques have been developed to yield precisely ordered oligophosphates which are soluble, hydrophilic, may be homogeneous, and may be prepared with a variety of functional groups.
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| Attorney, Agent or Firm: |
Loeb & Loeb LLP ;
Ram, Michael J. ;
Gluck, Peter J. ;
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| Primary / Asst. Examiners: |
Ambrose, Michael G.;
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| Maintenance Status: |
CC Certificate of Correction issued
View Certificate of Correction
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| INPADOC Legal Status: |
Show legal status actions
Family Legal Status Report
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| Foreign References: |
None
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| Other Abstract Info: |
CHEMABS 130(08)096032P
CHEMABS 130(08)096032P
DERABS C1999-105209
DERABS C1999-105209
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| Other References: |
Paxton, Raymond J.; Beatty, Barbara G.; Varadarajan,, Aravamuthan; and Hawthorne, M. Frederick; "Carboranyl Peptide--Antibody Conjugates for Neutron-Capture Therapy: Preparation, Characterization, and In Vivo Evaluation"; Bioconjugate Chem., vol. 3, 1992, p. 241.
(7 pages)
Cited by 3 patents
[ISI abstract]
Abraham, R.; Muller; Gabriel, D; "Boronated Antibodies for Neutron Capture Therapy"; Strahlenther. Onkol. 165 (1989), 148-151 (Nr. 2/3).
(4 pages)
Cited by 2 patents
Barth, R.F.; Mafune, N.; Alam, F.; Adams, D.M.; Soloway, A.H.; Makroglou, G.E.; Oredipe, O.A.; Blue, T.E.; Steplewski, Z.; "Conjugation, Purification and Characterization of Boronated Monoclonal Antibodies for Use in Neutron Capture Therapy"; Strahlenther, Onkol. 165 (1989), 142-145 (Nr. 2/3).
(4 pages)
Cited by 2 patents
Tamat, S.R.; Patwardhan, A.; Moore, D.E.; Kabral, A.; Bradstock, K.; Hersey, P.; Allen, B.J.; "Boronated Monoclonal Antibodies for Potential Neutron Capture Therapy of Malignant Melanoma and Leukaemia"; Strahlenther. Onkol. 165 (1989), 145-147 (Nr. 2/3).
(3 pages)
Cited by 2 patents
Varadarajan, Aravamuthan; Hawthorne, M. Frederick; "Novel Carboranyl Amino Acids and Peptides: Reagents for Antibody Modification and Subsequent Neutron-Capture Studies"; Bioconjugate Chem., vol. 2, No. 4, 1991, p. 242.
(12 pages)
Cited by 4 patents
[ISI abstract]
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