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 Title: |
US5882881:
Inhibition of cyst formation by cytoskeletal specific drugs
[ Derwent Title ]
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| Country: |
US United States of America
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| Inventor: |
Woo, David D. L.; Los Angeles, CA
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
1999-03-16
/ 1998-01-09
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| Application Number: |
US1998000004804
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| IPC Code: |
Advanced:
C12N 5/06;
Core:
more...
IPC-7:
C12N 5/00;
C12Q 1/02;
C12Q 1/10;
C12Q 1/24;
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| ECLA Code: |
C12N5/06B12K;
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| U.S. Class: |
Current:
435/030;
435/004;
435/029;
435/034;
435/039;
435/041;
435/325;
435/354;
435/369;
435/395;
435/402;
436/063;
514/462;
514/629;
540/478;
549/345;
Original:
435/030;
435/029;
435/034;
435/004;
435/041;
435/039;
435/240.2;
435/240.23;
436/063;
514/462;
514/629;
540/478;
549/345;
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| Field of Search: |
435/030,29,34,4,41,39,240.2,240.23
436/063
514/462,629
540/4.78
549/345
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| Government Interest: |
STATEMENT OF UNITED STATES GOVERNMENT SUPPORT
Certain aspects of this invention were made with United States government funding under NIH Grant No. DK 40700. The United States government has certain rights in these aspects of the invention in the United States.
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| Priority Number: |
| 1998-01-09 |
US1998000004804 |
| 1995-05-22 |
US1995000406910 |
| 1992-09-25 |
US1992000951270 |
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| Abstract: |
The invention provides a method of producing a culture of polycystic kidney cells which form cysts in vitro. A cell culture of polycystic kidney cells is also provided. A method for screening an agent in vitro to determine the effectiveness of the agent in treating polycystic kidney disease is disclosed. Further, a method of treating a mammal having polycystic kidney disease by administering a pharmaceutical composition is provided.
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| Attorney, Agent or Firm: |
Knobbe, Martens, Olsen & Bear LLP ;
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| Primary / Asst. Examiners: |
Leary, Louise N.;
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| INPADOC Legal Status: |
None
Family Legal Status Report
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| Parent Case: |
This application is a continuation of prior application Ser. No. 08/406,910 filed May 22, 1995, now U.S. Pat. No. 5,789,189, which is a Section 371 application of International Application No. PCT/US93/09124 filed on Sep. 24, 1993, and a continuation in part of Ser. No. 07/951,270 filed Sep. 25, 1992.
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| Designated Country: |
AU CA EP JP US DE ES FR GB IT
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| Family: |
Show 7 known family members
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First Claim:
Show all 30 claims |
What is claimed is:
1. A method of producing a culture of cells which form cysts in vitro, comprising:
- preparing a suspension of cells that form cysts in vivo in a medium suitable for the maintenance of said cells; and
- culturing said cells on a solid phase which substantially prevents the formation of a layer of said cells on the surface of said solid phase.
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| Background / Summary: |
Show background / summary
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| Drawing Descriptions: |
Show drawing descriptions
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| Description: |
Show description
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| Forward References: |
Show 4 U.S. patent(s) that reference this one
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| Foreign References: |
None
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| Other Abstract Info: |
CHEMABS 121(07)073915D
DERABS C1994-135601
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| Other References: |
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[ISI abstract]
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[ISI abstract]
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[ISI abstract]
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Cited by 10 patents
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(3 pages)
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(13 pages)
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(9 pages)
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(7 pages)
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(10 pages)
[ISI abstract]
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[ISI abstract]
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