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Title: |
US5891192:
Ion-implanted protein-coated intralumenal implants
[ Derwent Title ]

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Country: |
US United States of America

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Inventor: |
Murayama, Yuichi; Pacific Palisades, CA
Vinuela, Fernando; Pacific Palisades, CA
Suzuki, Yoshiaki; Wako, Japan
Iwaki, Masaya; Wako, Japan

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Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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Published / Filed: |
1999-04-06
/ 1997-05-22

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Application Number: |
US1997000861994

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IPC Code: |
Advanced:
A61L 27/34;
A61L 31/10;
A61L 33/12;
A61B 17/12;
Core:
A61L 27/00;
A61L 31/08;
A61L 33/00;
more...
IPC-7:
A61F 2/06;

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ECLA Code: |
A61L27/34+C08L89/00; A61L31/10+C08L89/00; A61L33/12A; A61L33/12F; A61L33/12R;

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U.S. Class: |
Current:
623/001.48;
Original:
623/001;

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Field of Search: |
623/001,2,11,12,66
428/410
427/002

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Priority Number: |
| 1997-05-22 |
US1997000861994 |

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Abstract: |
Ion-implanted protein-coated occlusion coils are described which have essentially the same dimensions as untreated coils and exhibit altered surface properties, e.g., thrombogenicity, endothelial cellular migration and adhesion, relative to untreated coils thus making them particularly useful in treating wide-necked brain aneurysms.

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Attorney, Agent or Firm: |
Morrison & Foerster, LLP ;

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Primary / Asst. Examiners: |
Isabella, David J.;

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INPADOC Legal Status: |
Show legal status actions
Family Legal Status Report

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Designated Country: |
AL AM AP AT AZ BA BB BG BR BY CA CH CN CU CZ DE DK EA EE EP ES FI GB GE GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR

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Family: |
Show 3 known family members

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First Claim:
Show all 20 claims |
We claim:
1. An intralumenal implant comprising a body of a biocompatible material and an ion-implanted protein coating on the body.

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Background / Summary: |
Show background / summary

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Drawing Descriptions: |
Show drawing descriptions

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Description: |
Show description

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Forward References: |
Show 35 U.S. patent(s) that reference this one

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Foreign References: |
None

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Other Abstract Info: |
CHEMABS 130(03)029279M
DERABS C1999-059716

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Other References: |
Ahuja et al., "Platinum coil coatings to increase thrombogenicity: A preliminary study in rabbits" AJNR (Jul./Aug. 1993) 14:794-798.
(5 pages)
Cited by 7 patents
[ISI abstract]
Dawson et al., "Treatment of experimental aneurysms using collagen-coated microcoils" J. Neurosurgery (1995) 36(1):133-139.
(7 pages)
Cited by 3 patents
[ISI abstract]
Iwaki, M., "Formation of metal surface layers with high performance by ion implantation" Nucl. Inst. Meth. Phys. Res. B37/38 (1989) Elsevier Science Publishers, Amsterdam, pp. 661-666.
(6 pages)
Murayama et al., "New surface modification of electrically detachable oil (GDC) by ion implantation into proteins" Kobunshi Gakkai Yokoshu (Polymer Preprints, Japan) (1996) 45(3):310. English translation enclosed.
Suzuki et al., "Cell adhesion control by ion implantation into extra-cellular matrix" Nucl. Instr. and Meth. in Phys. Res. B (1994) 91:588-592.
(5 pages)
[ISI abstract]
Suzuki et al., "Ion implantation into collagen for the subsrate of small diameter artificial grafts" Kobunshi Gakkai Yokoshu (Polymer Preprints, Japan) (1996) 45(3):310. English translation enclosed.

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