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 Title: |
US5968731:
Apparatus for automated testing of biological specimens
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| Country: |
US United States of America
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| Inventor: |
Layne, Scott P.; Los Angeles, CA
Beugelsdijk, Tony J.; Los Alamos, NM
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
1999-10-19
/ 1996-12-10
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| Application Number: |
US1996000764721
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| IPC Code: |
Advanced:
G01N 35/00;
Core:
more...
IPC-7:
C12Q 1/70;
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| ECLA Code: |
G01N35/00G5; G01N35/00R; S01N35/00D9; S01N35/00G5A;
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| U.S. Class: |
Current:
435/005;
422/063;
422/064;
422/065;
422/066;
422/067;
422/068.1;
422/082.09;
435/007.1;
435/007.92;
436/043;
436/047;
436/048;
436/051;
436/063;
436/180;
Original:
435/005;
435/007.1;
435/007.92;
436/043;
436/047;
436/048;
436/051;
436/063;
436/180;
422/063;
422/064;
422/065;
422/066;
422/067;
422/068.1;
422/082.09;
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| Field of Search: |
435/005,7.1,7.92
436/043,47,48,51,63,180
422/063-67,68.1,82.09
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| Government Interest: |
GOVERNMENT LICENSING RIGHTS
The U.S. Government has a paid-up license in this invention and the right in limited circumstances to require the patent owner to license others on reasonable terms as provided by the terms of Grant No. 009634 awarded by UC Los Alamos National Scientific Lab.
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| Priority Number: |
| 1996-12-10 |
US1996000764721 |
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| Abstract: |
An apparatus for performing automated testing of infections biological specimens is disclosed. The apparatus comprise a process controller for translating user commands into test instrument suite commands, and a test instrument suite comprising a means to treat the specimen to manifest an observable result, and a detector for measuring the observable result to generate specimen test results.
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| Attorney, Agent or Firm: |
Oppenheimer Wolff & Donnelly LLP ;
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| Primary / Asst. Examiners: |
Stucker, Jeffrey;
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| INPADOC Legal Status: |
Show legal status actions
Family Legal Status Report
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| Parent Case: |
CROSS REFERENCE TO RELATED APPLICATIONS
This application is related to the following, which are hereby incorporate by reference;
- application Ser. No. 08/764,719, now U.S. Pat. No. 5,841,975 entitled "APPARATUS FOR TESTING FOR INFECTION BY A RETROVIRUS," by Scott P. Layne, M.D., and Tony J. Beugelsdijk, Ph.D., M.B.A., and assigned to the assignee of this application; and
- application Serial No. 08/764,721, entitled "METHOD AND APPARATUS FOR GLOBALLY-ACCESSIBLE AUTOMATED TESTING," by Scott P. Layne, M.D., and Tony J. Beugelsdijk, Ph.D., and assigned to the assignee of this application.
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| Designated Country: |
AL AM AP AT AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE EP ES FI GB GE GH HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT
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| Family: |
Show 3 known family members
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First Claim:
Show all 24 claims |
What is claimed is:
1. An automated apparatus for treating a biological specimen with reagents for infectivity assays to manifest an observable test result, comprising:
- an automated inoculation instrument module for exposing the specimen to a viral assay;
- an automated specimen preparation instrument module for applying the treated specimen to a surface so adapted to permit detecting the observable result, for applying indicator cells, and for applying liquid reagents;
- an automated support module for transporting the biological specimen between the automated inoculation instrument module and the automated specimen preparation instrument module including means for effecting multiple assays on the same specimen, at least two of which assays are an infectivity assay, a cytotoxicity assay, or a biochemical assay; and
- means for controlling at least some of the modules by a remote client, the remote client communicating with the modules through an Internet link to control the performance of multiple assays on the same specimen.
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| Background / Summary: |
Show background / summary
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| Drawing Descriptions: |
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| Description: |
Show description
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| Forward References: |
Show 25 U.S. patent(s) that reference this one
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| Foreign References: |
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| Other Abstract Info: |
CHEMABS 129(04)038353N
DERABS C1998-348697
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| Other References: |
Scott P. Layne, M.D., et al., "Factors Underlying Spontaneous Inactivation and Susceptibility to Neutralization of Human Immunodeficiency Virus," Virology, (189), 1992, pp. 695-714.
(20 pages)
Cited by 3 patents
[ISI abstract]
Scott P. Layne, M.D. et al., "Quantifying the Infectivity of Human Immunodeficiency Virus," Proc. Natl. Acad. Sci., vol. 86, pp. 4644-4648, Jun. 1989, Immunology.
(5 pages)
Cited by 3 patents
Tony J. Beugelskijk, Ph.D. et al., "Contaminant Analysis Automation," Environmental Testing and Analysis, vol.2, No. 2, Mar./Apr. 1993, pp. 68-76.
F.A. Settle, Jr., et al., "The Contaminant Analysis Automation Project," American Laboratory, Apr. 1995.
"The Contaminant Analysis Automation Project," Los Alamos National Laboratory, Apr. 1995, pp. 1-15.
T.J. Beugelsdijk et al. "The Standard Laboratory Module . . . Laboratory" Chemometrics and Intelligent Laoratory Systems 21:207-214 (1993) (Exhibit 8).
(8 pages)
Cited by 3 patents
[ISI abstract]
J. Gentsch, "Flexible Laboratory Automation to . . . 90s" Chemometrics and Intelligent Systems 21:229-233(1993) (Exhibit 9).
(5 pages)
Cited by 5 patents
[ISI abstract]
T. Ikeda & F. Takahata "Total Clinical Laboratory . . . Automation" Hitachi Review 41(4)(1992) (Exhibit 10).
PCT International Search Report, PCT/US 97/22543 dated May, 12, 1998 (Exhibit 11).
Chumbley et al. "Computer Networked Scanning Electron Microscope for Teaching, Research, and Industry Application" Microscopy Research and Technique, vol. 32, No. 4 (Nov. 1 1995), pp. 330-336. Abstract Only.
(7 pages)
Cited by 2 patents
[ISI abstract]
Tersmette et al. "Detection and Subtyping of HIV-1 Isolates with a Panel of Characterized Monoclonal Antibodies to HIV p24gag " Virology, vol. 171, No. 1 (1989), pp. 149-155. QR1.V5.
(7 pages)
Cited by 2 patents
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