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 Title: |
US6011995:
Endovascular device for hyperthermia and angioplasty and method for using the same
[ Derwent Title ]
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| Country: |
US United States of America
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| Inventor: |
Guglielmi, Guido; Santa Monica, CA
Ji, Cheng; Los Angeles, CA
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
2000-01-04
/ 1997-12-29
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| Application Number: |
US1997000998589
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| IPC Code: |
Advanced:
A61B 18/08;
A61N 1/28;
A61N 1/40;
Core:
A61B 18/04;
A61N 1/20;
more...
IPC-7:
A61B 17/38;
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| ECLA Code: |
A61B18/08B; A61N1/28; A61N1/40T;
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| U.S. Class: |
Current:
607/099;
606/029;
607/113;
Original:
607/099;
606/029;
607/113;
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| Field of Search: |
607/098-99,113
606/027,28-31
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| Priority Number: |
| 1997-12-29 |
US1997000998589 |
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| Abstract: |
Hyperthermic treatment of tissue such as cancer tumors, is realized by providing an ohmic heating element on the distal tip of a catheter endovascularly inserted upstream of the tissue. Electrical power is provided to the element for a selected time and degree to raise the temperature of blood to a thermally mediating level such as 42° C., but not to heat the blood so that distal tissues downstream are adversely affected. The element comprises a helical coil heater disposed proximate to the end of a catheter and within an expandable cage. The cage can be selectively deployed by expanding it to maintain the coil out of contact with the vessel walls while still allowing free blood flow. Alternatively a guidewire within an expandable cage can be disposed within the same catheter wherein the heating coil has been wound onto the guidewire or the guidewire is uninsulated at that portion within the cage serves as an electrode to directly heat the blood. Angioplasty without blood flow blockage is realized by expanding a cage instead of a balloon on the catheter. The cage can be selectively expanded by withdrawal of a guidewire temporarily coupled to the catheter tip. The cage can widen the narrowed vascular lumen while still allowing free blood flow and/or contrast agent, and it avoids the risk of balloon deflation failure. The expandable cage can be detachable and implantable as a stent.
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| Attorney, Agent or Firm: |
Dawes, Daniel L. ;
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| Primary / Asst. Examiners: |
Cohen, Lee; Gibson, Roy
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| INPADOC Legal Status: |
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| Family: |
None
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First Claim:
Show all 5 claims |
We claim:
1. An apparatus for hyperthermic treatment of tissue comprising:
- a catheter having a longitudinal lumen;
- an elongated member having a distal and proximal end, said distal end adapted to be positioned proximate to said tissue and thermally coupled thereto, said elongated member telescopically disposed in said lumen of said catheter; and
- a ohmic heating element disposed on said elongated member at or proximate to said distal end, said ohmic heating element adapted to be in direct contact with fluid normally flowing to said tissue so that said tissue is subjected to a controlled amount of heat at a selected temperature for a selected amount of time,
- wherein said tissue is supplied with fluid by a vessel having a vascular wall; and a radially extensible cage structure for selectively maintaining said ohmic heating element in a spaced apart relationship from said vascular wall, and
- wherein said elongated member is variably coupled to said catheter so that an action applied to said elongated member is adapted to reversibly longitudinally elongate or contract at least a distal portion of said catheter and thereby to reversibly and radially extend or contract said cage structure.
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| Background / Summary: |
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| Drawing Descriptions: |
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| Description: |
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| Forward References: |
Show 59 U.S. patent(s) that reference this one
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