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 Title: |
US6066133:
Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
[ Derwent Title ]
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| Country: |
US United States of America
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| Inventor: |
Guglielmi, Guido; Santa Monica, CA
Sepetka, Ivan; Redwood City, CA
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
2000-05-23
/ 1997-10-06
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| Application Number: |
US1997000944826
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| IPC Code: |
Advanced:
A61B 17/12;
A61B 18/14;
A61B 17/00;
A61B 18/12;
A61B 19/00;
Core:
more...
IPC-7:
A61B 18/08;
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| ECLA Code: |
A61B17/12P; A61B18/14; A61B18/14V; A61M25/09;
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| U.S. Class: |
Current:
606/032;
606/041;
606/108;
606/191;
Original:
606/032;
606/041;
606/108;
606/191;
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| Field of Search: |
606/032,41,49,28,108,191
600/529,585
604/104
607/122
623/001,12
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| Priority Number: |
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| Abstract: |
An artery, vein, aneurysm, vascular malformation or arterial fistula is occluded through endovascular occlusion by the endovascular insertion of a platinum wire and/or tip into the vascular cavity. The vascular cavity is packed with the tip to obstruct blood flow or access of blood in the cavity such that the blood clots in the cavity and an occlusion if formed. The tip may be elongate and flexible so that it packs the cavity by being folded upon itself a multiple number of times, or may pack the cavity by virtue of a filamentary or fuzzy structure of the tip. The tip is then separated from the wire mechanically or by electrolytic separation of the tip from the wire. The wire and the microcatheter are thereafter removed leaving the tip embedded in the thrombus formed within the vascular cavity. Movement of wire in the microcatheter is more easily tracked by providing a radioopaque proximal marker on the microcatheter and a corresponding indicator marker on the wire. Electrothrombosis is facilitate by placing the ground electrode on the distal end of the microcatheter and flowing current between the microcatheter electrode and the tip.
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| Attorney, Agent or Firm: |
Dawes, Daniel L. ;
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| Primary / Asst. Examiners: |
Cohen, Lee;
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| INPADOC Legal Status: |
None
Family Legal Status Report
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| Related Applications: |
| Application Number |
Filed |
Patent |
Pub. Date |
Title |
|---|
| US1997000801795 | 1997-02-14 |
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1999-01-05
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Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
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| US1995000485821 | 1995-06-06 |
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| US1994000311508 | 1994-09-23 |
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1996-07-30
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Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
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| US1992000840211 | 1992-02-24 |
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1994-10-11
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In an endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
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| US1990000492717 | 1990-03-13 |
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1992-06-16
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Endovascular electrolytically detachable guidewire tip for the electroformation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
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| Parent Case: |
This application is a continuation of application Ser. No. 08/801,795 filed Feb. 14, 1997, issued as U.S. Pat. No. 5,855,578, which in turn was a continuation of application Ser. No. 08/485,821, filed Jun. 6, 1995, now abandoned, and which in its turn was a continuation-in-part application of application Ser. No. 07/492,717, filed Mar. 13, 1990, issued as U.S. Pat. No. 5,122,136.
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| Designated Country: |
BB BR KP LK MG MW SD SU BE CH DK FR GB IE IT LI LU MC NL SE BG CS KR PL RO RU
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| Family: |
Show 163 known family members
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First Claim:
Show all 47 claims |
We claim:
1. An apparatus for forming an occlusion within a body cavity comprising:
- a wire adapted to be disposed near an opening into said body cavity;
- a separable distal tip of said wire adapted for disposition into said body cavity to form said occlusion within said body cavity about said distal tip; and
- a selectively detachable coupling between said distal tip and said wire characterized by detachment of said distal tip from said wire without necessarily displacing either said distal tip or said wire during detachment to leave said distal tip within said body cavity with said occlusion being formed within said body cavity,
- whereby said body cavity is occluded by said distal tip, and an occlusion is formed by use of said tip without necessarily altering desired placement of said distal tip during detachment or applying any force by said distal tip to any surface within said body cavity by reason of said detachment.
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| Background / Summary: |
Show background / summary
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| Drawing Descriptions: |
Show drawing descriptions
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| Description: |
Show description
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| Forward References: |
Show 6 U.S. patent(s) that reference this one
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| Foreign References: |
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| Other Abstract Info: |
DERABS G1991-295348
DERABS G1993-288069
DERABS G1999-619574
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| Other References: |
Target Therapeutics, "History of the Guglielmi Detachable Coil," History of the GDC, pp. 1-6 Oct. 1995.
Guglielmi et al., "Intravascular Electrothrombosis in Experimentally Induced Vascular Malformation," Assoziazone Italiani di Neuroradiologia, Sep. 29-30, 1983, pp. 139-146.
Sadato et al., "Immediately Detachable Coil for Aneurysms Treatment," ANJR 16: 1459-1462 Aug. 1995.
(4 pages)
Cited by 13 patents
[ISI abstract]
Mullan, "Eperiences with Surgical Thrombosis of Intracranial Berry Aneurysms and Carotid Cavernous Fistulas", J. Neurosurg., vol. 41, Dec. 1974, pp. 657-670.
(14 pages)
Cited by 11 patents
Hosobuchi, "Electrothrombosis Carotid-Cavernous Fistula", J. Neurosurg., vol. 42, Jan. 1975, pp. 76-85.
(10 pages)
Cited by 13 patents
Araki et al., "Electrically Induced Thrombosis for the Treatment of Intracranial Aneurysms and Angiomas", Excerpta Medica International Congress Series, Amsterdam 1965, vol. 110, pp. 651-654.
Sawyer et al., "Bio-Electric Phenomena as an Etiological Factor in Intravascular Thrombosis", Am., J. Physiol., vol. 175, pp. 103-107 (1953).
J. Piton et al., "Selective Vascular Thrombosis Induced by a Direct Electrical Current; Animal Experiments", J. Neuroradiology, vol. 5, pp. 139-152 (1978).
(14 pages)
Cited by 13 patents
Anderson et al, "Transcathter Intravascular Coil Occulsion of Experimental Arteriovenous Fistulas", AM. J. Roentgenol. vol. 129, pp. 795-798, Nov. 1977.
(4 pages)
Cited by 62 patents
Zuniga et al, "A New Device for Safe Delivery of Stainless Steel Coils" Radiology vol. 136, pp. 230-231, Jul. 1980.
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