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Title: US6090380: Treatment of rheumatoid arthritis by oral administration of pooled human immunoglobulin
[ Derwent Title ]


Country: US United States of America

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11 pages

 
Inventor: Weisbart, Richard; Los Angeles, CA

Assignee: Research Corporation Technologies, Inc., Tucson, AZ
other patents from RESEARCH CORPORATION TECHNOLOGIES, INC. (471735) (approx. 327)
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Published / Filed: 2000-07-18 / 1995-05-22

Application Number: US1995000445595

IPC Code: Advanced: C07K 16/00;
Core: more...
IPC-7: A61K 39/395; C07K 16/00; C07K 16/06; C07K 16/44;

ECLA Code: C07K16/00;

U.S. Class: Current: 424/130.1; 424/176.1; 424/177.1; 424/810; 530/386; 530/387.1; 530/389.1; 530/390.1; 530/390.5; 530/868;
Original: 424/130.1; 424/176.1; 424/177.1; 424/810; 530/868; 530/386; 530/387.1; 530/389.1; 530/390.1; 530/390.5;

Field of Search: 424/130.1,176.1,177.1,810 530/868,386,387.1,389.1,390.1,390.5

Priority Number:
1995-05-22  US1995000445595
1994-01-12  US1994000180229

Abstract: Pooled human immunoglobulin may be administered orally to rheumatoid arthritis patients to treat the rheumatoid arthritic condition of those patients. Oral administration of pooled human immunoglobulin can result in significant clinical improvement in the level of disease activity in patients with rheumatoid arthritis.

Attorney, Agent or Firm: Scully, Scott, Murphy & Presser ;

Primary / Asst. Examiners: Schwadron, Ronald B.;

INPADOC Legal Status: Show legal status actions

       
Related Applications:
Application Number Filed Patent Pub. Date  Title
US1994000180229 1994-01-12       


       
Parent Case:     This is a continuation of Ser. No. 08/180,229 filed on Jan. 12, 1994 (now abandoned).

Family: None

First Claim:
Show all 6 claims
What is claimed is:     1. A method of treating adult autoimmune rheumatoid arthritis in a patient comprising orally administering to said patient an immunoglobulin composition consisting essentially of pooled human polyclonal IgG antibodies in an amount sufficient to provide a clinically observable improvement in the rheumatoid arthritis of said patient.

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U.S. References: Go to Result Set: All U.S. references   |  No patents reference this one   |   Backward references (4)   |   Citation Link

Buy
PDF
Patent  Pub.Date  Inventor Assignee   Title
Buy PDF- 5pp US4477432  1984-10 Hardie  Cutter Laboratories, Inc. Oral immune globulin
Buy PDF- 42pp US5242691  1993-09 Beck  Stolle Research & Development Corporation Anti-inflammatory factor, method of isolation, and use
Buy PDF- 13pp US5681571  1997-10 Holmgren et al.  Duotol AB Immunological tolerance-inducing agent
Buy PDF- 13pp USRE33565  1991-04 Stolle et al.  Stolle Research and Development Corporation Prevention and treatment of rheumatioid arthritis
       
Foreign References: None

Other References:
  • Silverman et al., J. Rheumatol., 21: 2353-2358, 1994 Alarcow, "Rheumatology and Immunology", Chapter 28, Second Edition, Harcourt Brace Jovanovich, 1986.
  • Silverman et al., Arth and Rheum, 33:1015-1022, 1990.
  • Edginston, Bio/Technology, 10: 383-386, 388, 389, 1992.
  • Herman et al., Annu. Rev. Immunol., 9:745-772 (1991).
  • Drake et al., J. Clin. Immunol., 12P149-162 (1992).
  • Takei et al., J. Clin. Invest., 91:602-607 (1993).
  • Rich, J. Clin. Invest., 91-378 (1993).
  • Sandoglobulin Brochure, (1991).
  • Trentham et al., Science, 261:1727 (1993).
  • Weiner et al., Science, 259:1321 (1993).
  • Palliard et al., Science, 253:325 (1991).


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