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 Title: |
US6110702:
PSA positive regulating (PSAR) sequences and uses thereof
[ Derwent Title ]
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| Country: |
US United States of America
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| Inventor: |
Pang, Shen; Van Nuys, CA
Belldegrun, Arie S.; Los Angeles, CA
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
2000-08-29
/ 1997-03-27
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| Application Number: |
US1997000828972
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| IPC Code: |
Advanced:
C12N 9/64;
C12N 15/85;
A61K 48/00;
Core:
more...
IPC-7:
C07H 21/04;
C12N 15/00;
C12P 21/04;
C12P 21/06;
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| ECLA Code: |
C12N9/64F2C21M34; C12N15/85; K61K48/00; M12N207/00; M12N830/00A1; M12N830/00C; M12N830/85;
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| U.S. Class: |
Current:
435/069.1;
435/070.1;
435/320.1;
435/455;
435/466;
536/024.1;
Original:
435/069.1;
435/070.1;
435/320.1;
435/455;
435/466;
536/024.1;
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| Field of Search: |
536/24.1
514/044
435/69.1,70.1,455,466,320.1
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| Priority Number: |
| 1997-03-27 |
US1997000828972 |
| 1996-03-27 |
US1996000014201P |
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| Abstract: |
The present invention provides an isolated nucleic acid molecule which is a PSA positive regulatory sequence (PSAR). This molecule has been deposited with the ATCC. In one embodiment of the invention, the molecule comprises a nucleic acid sequence shown in FIG. 4 (SEQ ID NO: 3).
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| Attorney, Agent or Firm: |
Mandel & Adriano ;
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| Primary / Asst. Examiners: |
Eyler, Yvonne;
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| INPADOC Legal Status: |
Show legal status actions
Family Legal Status Report
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| Parent Case: |
This application is based on a provisional application, U.S. Serial No. 60/014,201, filed Mar. 27, 1996.
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| Designated Country: |
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE CA EP IL JP
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| Family: |
Show 5 known family members
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First Claim:
Show all 40 claims |
What is claimed is:
1. An isolated nucleic acid molecule which is designated PSAR, consisting of SEQ ID NO: 3.
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| Background / Summary: |
Show background / summary
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| Drawing Descriptions: |
Show drawing descriptions
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| Description: |
Show description
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| Forward References: |
Show 1 U.S. patent(s) that reference this one
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| Foreign References: |
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| Other Abstract Info: |
CHEMABS 127(22)304111F
DERABS C1997-489654
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| Other References: |
Pang, S. et al., "Identification of a Positive Regulatory Element Responsible for Tissue-specific Expression of Prostate-specific Antigen," Cancer Research, 57:459-499, Feb. 1, 1997. (Exhibit 2).
Dannull, J. et al., "Development of Gene Therapy for Prostate Cancer Using a Novel Promoter of Prostate-specific Antigen," British Journal of Urology, 79:97-103, 1997 (Exhibit 3).
(7 pages)
Cited by 2 patents
[ISI abstract]
Cleutjens, Kitty B.J.M. et al., "An Androgen Response Element in a Far Upstream Enhancer Region Is Essential for High, Androgen-Regulated Activity of the Prostate-specific Antigen Promoter," Molecular Endocrinology, 11(2):148-161, 1997. (Exhibit 4).
(14 pages)
Cited by 7 patents
[ISI abstract]
Pang et al., 1995, Human Gene Therapy, 6:1417-1426.
(10 pages)
Cited by 14 patents
[ISI abstract]
Riegman et al., 1991, Molecular Endocrinology, 5(12):1921-1930.
(10 pages)
Cited by 15 patents
[ISI abstract]
Bacchetti and Graham, 1977, PNAS USA, 74:1590-1594.
(5 pages)
Cited by 16 patents
Li and Steshenko, 1992, Journal of Immunology, 148(3):788-94.
(7 pages)
Cited by 16 patents
[ISI abstract]
Kay et al., 1991, J. Exp. Med., 173:775-778.
(4 pages)
Cited by 20 patents
[ISI abstract]
Shuur et al., 1996, J. Biol. Chem. 271:7043-7051.
Vile et al., 1994, Cancer Res. 54:6228-6234.
(7 pages)
Cited by 18 patents
[ISI abstract]
el-Shirbiny, A.M., 1994, Adv. Clin. Chem. 31:99-133.
(35 pages)
Cited by 26 patents
[ISI abstract]
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