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 Title: |
US6150136:
Nucleotide sequence encoding oligodendrocyte-specific protein
[ Derwent Title ]
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| Country: |
US United States of America
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| Inventor: |
Bronstein, Jeff M.; Santa Monica, CA
Seitz, Robert S.; Huntsville, AL
Lallone, Roger L.; Birmingham, AL
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| Assignee: |
The Regents of the University of California, Oakland, CA
Research Genetics, Inc., Huntsville, AL
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
2000-11-21
/ 1998-05-22
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| Application Number: |
US1998000084079
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| IPC Code: |
Advanced:
C07K 14/47;
Core:
C07K 14/435;
IPC-7:
C07H 21/04;
C12N 5/00;
C12N 15/00;
C12N 15/09;
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| ECLA Code: |
C07K14/47A5;
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| U.S. Class: |
Current:
435/069.3;
435/320.1;
435/325;
536/023.5;
Original:
435/069.3;
435/320.1;
435/325;
536/023.5;
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| Field of Search: |
435/320.1,325,69.3
536/23.5
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| Government Interest: |
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
This invention was made with Government support under Grant No. NS01596, awarded by the National Institutes of Health. The Government has certain rights in this invention.
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| Priority Number: |
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| Abstract: |
A protein consisting essentially of purified oligodendrocyte-specific protein or purified biologically active variants thereof, or a combination of purified oligodendrocyte-specific protein and biologically active variants thereof. A purified and isolated peptide having the sequence Ala-Lys-Tyr-Arg-Arg-Ala-Gln-Leu-Ala-Gly, residues 115-124 of SEQ ID NO:2.
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| Attorney, Agent or Firm: |
Farah, David A.Sheldon & Mak ;
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| Primary / Asst. Examiners: |
Navarro, Albert;
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| Maintenance Status: |
E1 Expired Check current status
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| INPADOC Legal Status: |
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Family Legal Status Report
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| Parent Case: |
CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a continuation-in-part of PCT application PCT/US96/18152, entitled OLIGODENDROCYTE-SPECIFIC PROTEIN AND METHOD FOR TREATING DISEASE, filed Nov. 13, 1996, and is a continutation-in-part of U.S. patent application Ser. No. 08/557,917, entitled OLIGODENDROCYTE-SPECIFIC PROTEIN AND METHOD FOR DIAGNOSING AND TREATING DISEASE, filed Nov. 14, 1995, now U.S. Pat. No. 5,756,300; both incorporated herein by reference in their entirety.
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| Designated Country: |
AL AM AP AT AZ BA BB BG BR BY CA CH CN CU CZ DK EE FI GE HU IL IS JP KE KG KP KR KZ LC LK LR LS LT DE ES FR GB IT
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| Family: |
Show 7 known family members
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First Claim:
Show all 9 claims |
What is claimed is:
1. An isolated DNA segment comprising SEQ ID NO: 1.
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| Background / Summary: |
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| Drawing Descriptions: |
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| Description: |
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| Foreign References: |
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| Other Abstract Info: |
DERABS C1997-289056
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| Other References: |
Sevier, E.D. et al., "Monoclonal Antibodies in Clinical Immunology," Clinical Chemistry 27(11):1797-1805 (1981).
(10 pages)
Cited by 283 patents
Xie, D. et al., "The oligodendroglial reaction to brain stab wounds: an immunohistochemical study," Journal of Neurocytology 24:435-448 (1995).
(14 pages)
Cited by 3 patents
[ISI abstract]
Schaeren-Wiemers, N. et al., "Identification of New Oligodendrocyte- and Myelin-Specific Genes by a Differential Screening Approach," Journal Of Neurochemistry 65(1):10-22, 1995.
(13 pages)
Cited by 2 patents
[ISI abstract]
Schaefer et al., "The C-DNA of COP, A novel oligodendrocyte-specific protein," Experientia 49:A66 (1993).
Buznikov, A. et al., "Cloning of the Human Oligodendrocyte-Specific Protein (OSP) Homologue," Depts. Of Neurology and Pharmarcology and the Brain Research Institute, UCLA School of Medicine, Los Angeles, CA-Abstact and Poster from Society of for Neuroscience Meeting, Nov. of 1996.
Pham--Dinh et al (Journal of Neurochemistry vol. 63 No. 6, pp. 2353-2356 Dec. 1994).
(4 pages)
Cited by 5 patents
[ISI abstract]
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