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 Title: |
US6232444:
Conserved anti-DNA antibody idiotype associated with nephritis in murine and human lupus
[ Derwent Title ]
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| Country: |
US United States of America
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| Inventor: |
Weisbart, Richard; Los Angeles, CA
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
2001-05-15
/ 1996-04-08
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| Application Number: |
US1996000629355
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| IPC Code: |
Advanced:
C07K 16/42;
Core:
more...
IPC-7:
C07K 16/42;
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| ECLA Code: |
C07K16/42K14;
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| U.S. Class: |
Current:
530/387.2;
435/327;
530/387.3;
530/868;
Original:
530/387.2;
435/327;
530/387.3;
530/868;
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| Field of Search: |
435/7.9,7.95,965,327
436/508,548
530/387.2,868,387.3
424/131.1,140.1
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| Priority Number: |
| 1996-04-08 |
US1996000629355 |
| 1990-01-29 |
US1990000471880 |
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| Abstract: |
Methods and antibody compositions are provided for the diagnosis and treatment of lupus nephritis. By employing B-cells of a lupus nephritis host with a fusion partner, antibodies can be obtained, which may serve as immunogens for the production of antiidiotypic antibodies, which may then be used for diagnosis and therapy of lupus nephritis.
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| Attorney, Agent or Firm: |
Gray Cary Ware & Freidenrich LLP ;
Haile, Lisa A. ;
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| Primary / Asst. Examiners: |
Saunders, David;
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| Foreign References: |
None
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| Other References: |
Herbert et al, Dictionary Of Immunology--3rd Ed., Blackwell Scientific Publications, p. 199, 1985.*
Weisbart et al., Arth, Rheum., 30 (4 Suppl.), S104, 1987.
Hahn et al., Journ. Immunol., 138, 2110-2119, 1987.
Livneh et al., Journ. Immunol., 138, 123-127, 1987.
Riott, Essential Immunology, Scientific Publications, Oxford UK, 1984, pp. 14-15, 5th Ed., Blackwell.
R.H. Weisbart et al., J. Immunol., 144, 2653-2658, 1990.
W.J. Herbert et al. (Eds.), Dictionary of Immunology, 3d Ed., Blackwell Sci. Pub., 1985, p. 106.
Dierksheide, ASM News, 53, 677-680, 1987.
Kalunian et al., Arth. & Rheum., 32, 513-522, 1989.
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