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 Title: |
US6248916:
Macromolecular structures for boron neutron-capture therapy
[ Derwent Title ]
>> View Certificate of Correction for this publication
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| Country: |
US United States of America
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| Inventor: |
Kane, Robert R.; Los Angeles, CA
Hawthorne, M. Frederick; Encino, CA
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| Assignee: |
Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
2001-06-19
/ 1999-01-05
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| Application Number: |
US1999000225608
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| IPC Code: |
Advanced:
A61K 41/00;
C07F 9/6596;
Core:
C07F 9/00;
more...
IPC-7:
C07F 9/02;
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| ECLA Code: |
A61K41/00Z4; C07F9/6596;
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| U.S. Class: |
Current:
558/072;
Original:
558/072;
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| Field of Search: |
514/064
424/181.1,657
558/072
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| Government Interest: |
This invention was made with support under Grant Numbers CA31753-09, CA53870-01 and CA09306-01 from the National Institutes of Health, U.S. Department of Health and Human Resources. Accordingly, the U.S. Government has certain rights in the invention.
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| Priority Number: |
| 1999-01-05 |
US1999000225608 |
| 1997-02-27 |
US1997000810333 |
| 1995-01-11 |
US1995000371563 |
| 1993-03-12 |
US1993000030920 |
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| Abstract: |
A general synthetic method has been developed for the rapid and efficient production of a variety of boron-rich macromolecules suitable for conjugation with inclusion in receptor-mediated delivery systems as well as other delivery systems. Preparation techniques have been developed to yield precisely ordered oligophosphates which are soluble, hydrophilic, may be homogeneous, and may be prepared with a variety of functional groups.
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| Attorney, Agent or Firm: |
Koppel & Jacobs ;
Ram, Michael J. ;
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| Primary / Asst. Examiners: |
Lambkin, Deborah C.;
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| Maintenance Status: |
CC Certificate of Correction issued
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| INPADOC Legal Status: |
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| Parent Case: |
This application is a divisional of Ser. No. 08/810,333, now U.S. Pat. No. 5,856,551 issued Jan. 5, 1999 which is a continuation of Ser. No. 08/371,563, filed Jan. 11, 1995 now abandoned which is a continuation of Ser. No. 08/030,920, filed Mar. 12, 1993 now abandoned.
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| Family: |
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First Claim:
Show all 14 claims |
What is claimed is:
1. A water soluble, straight chain boron-rich oligophosphate which comprises an ordered plurality of carborane monomer units, the carborane monomer units having two hydroxyl groups attached thereto, said carborane monomer units being linked by the hydroxyl groups to phosphate units, said boron-rich oligophosphate having alternating carborane units and phosphate units.
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| Background / Summary: |
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| Drawing Descriptions: |
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| Description: |
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