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 Title: |
US6277825:
Use of conantokins for treating pain
[ Derwent Title ]
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| Country: |
US United States of America
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| Inventor: |
Olivera, Baldomero M.; Salt Lake City, UT
McIntosh, J. Michael; Salt Lake City, UT
McCabe, R. Tyler; Salt Lake City, UT
Layer, Richard T.; Sandy, UT
Zhou, Li-Ming; Indianapolis, IN
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| Assignee: |
University of Utah Research Foundation, Salt Lake City, UT
Cognetix, Inc., Salt Lake City, UT
other patents from UNIVERSITY OF UTAH RESEARCH FOUNDATION (600050) (approx. 286)
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| Published / Filed: |
2001-08-21
/ 1999-07-20
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| Application Number: |
US1999000357141
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| IPC Code: |
Advanced:
C07K 14/435;
A61K 38/00;
Core:
more...
IPC-7:
A61K 38/00;
A61K 38/02;
C07K 5/00;
C07K 7/00;
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| ECLA Code: |
C07K14/435A;
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| U.S. Class: |
Current:
514/013;
514/002;
514/012;
530/326;
Original:
514/013;
514/002;
514/012;
530/326;
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| Field of Search: |
514/012,2,13,923
530/326
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| Priority Number: |
| 1999-07-20 |
US1999000357141 |
| 1999-04-01 |
US1999000283277 |
| 1996-12-06 |
US1996000762377 |
| 1996-07-22 |
US1996000684750 |
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| Abstract: |
The present invention is directed to the use of conantokin peptides, conantokin peptide derivatives and conantokin peptide chimeras, referred to collectively as conantokins, having 10-30 amino acids, including preferably two or more gamma-carboxyglutamic acid residues, for the treatment of neurologic and psychiatric disorders, such as pain, e.g., as an analgesic agent.
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| Attorney, Agent or Firm: |
Rothwell, Figg, Ernst & Manbeck, p.c. ;
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| Primary / Asst. Examiners: |
Davenport, Avis M.;
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| Maintenance Status: |
E1 Expired Check current status
CC Certificate of Correction issued
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| INPADOC Legal Status: |
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| Related Applications: |
| Application Number |
Filed |
Patent |
Pub. Date |
Title |
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| US1999000283277 | 1999-04-01 |
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| US1996000762377 | 1996-12-06 |
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| US1996000684750 | 1996-07-22 |
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| Parent Case: |
CROSS REFERENCE TO RELATED APPLICATIONS
The present application is a continuation-in-part of application Ser. No. 09/283,277 filed Apr. 1, 1999, which is a continuation of application Ser. No. 09/142,076 filed Feb. 10, 1999, which in turn is a 371 of international application PCT/US97/12652 filed Jul. 21, 1997, which in turn is a continuation-in-part of application Ser. No. 08/762,377 filed Dec. 6, 1996, which in turn is a continuation-in-part of application Ser. No. 08/684,750 filed Jul. 22, 1996, all incorporated herein by reference.
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| Designated Country: |
AL AM AP AZ BA BB BG BR BY CA CN CU CZ EE GE HU IL IS JP KE KG KP KR KZ LC AT BE CH DE DK ES FI FR GB GR IE IT LI
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| Family: |
Show 10 known family members
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First Claim:
Show all 9 claims |
What is claimed is:
1. A method for treating disorders in which the pathophysiology involves excessive excitation of nerve cells by excitatory amino acids or agonists of the NMDA receptor which comprises administering to a patient in need thereof a therapeutically effective amount of an active agent selected from the group consisting of a conantokin peptide, a conantokin peptide derivative or a conantokin peptide chimera, wherein said disorder is pain.
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| Background / Summary: |
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| Drawing Descriptions: |
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| Description: |
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| Forward References: |
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