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 Title: |
US6300104:
Secretory immunoglobulin produced by single cells and methods for making and using same
[ Derwent Title ]
>> View Certificate of Correction for this publication
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| Country: |
US United States of America
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| Inventor: |
Morrison, Sherie L.; Los Angeles, CA
Chintalacharuvu, Kote R.; Los Angeles, CA
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| Assignee: |
The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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| Published / Filed: |
2001-10-09
/ 1998-06-10
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| Application Number: |
US1998000095385
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| IPC Code: |
Advanced:
A61K 39/395;
A61P 37/04;
C07K 16/00;
C12P 21/04;
A61K 38/00;
Core:
A61P 37/00;
more...
IPC-7:
A61K 39/29;
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| ECLA Code: |
A61K39/395S; C07K16/00;
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| U.S. Class: |
Current:
435/070.21;
424/133.1;
424/141.1;
424/147.1;
435/070.1;
435/070.2;
435/320.1;
435/326;
435/328;
435/339;
530/387.1;
530/808;
Original:
435/070.21;
435/070.1;
435/070.2;
435/320.1;
435/326;
435/328;
435/339;
424/141.1;
424/147.1;
424/133.1;
530/387.1;
530/808;
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| Field of Search: |
435/70.21,320.1,70.2,70.1,326,328,339
424/147.1,141.1,133.1
530/387.1,808
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| Government Interest: |
This invention was made with government support under grants CA16858, A129470 and A139187, awarded by the National Institutes of Health. The United States government has certain rights in this invention.
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| Priority Number: |
| 1998-06-10 |
US1998000095385 |
| 1997-06-19 |
US1997000050969P |
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| Abstract: |
Disclosed is a method of producing secretory Ig molecules. The method comprises transfecting a cell producing an Ig with a polynucleotide encoding an SC to fonn SC transfected Ig producing cells. Secretory Ig molecules, such as secretory IgA, can be used to treat or prevent infection.
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| Attorney, Agent or Firm: |
Gates & Cooper LLP ;
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| Primary / Asst. Examiners: |
Allen, Marianne P.; Zeman, Mary K.
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| Maintenance Status: |
CC Certificate of Correction issued
View Certificate of Correction
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| INPADOC Legal Status: |
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Family Legal Status Report
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| Parent Case: |
This application is based on U.S. provisional application serial No. 60/050,969, filed Jun. 19, 1997, the contents of which are incorporated herein by reference. Throughout this application various publications are referenced. The disclosures of these publications in their entireties are hereby incorporated by reference into this application in order to more fully describe the state of the art to which this invention pertains.
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| Designated Country: |
AL AM AP AT AZ BA BB BG BR BY CA CH CN CU CZ DE DK EA EE EP ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK
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| Family: |
Show 5 known family members
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First Claim:
Show all 19 claims |
What is claimed is:
1. A method of producing secretory Ig (sIg) molecules comprising transfecting a non-plant cell producing an Ig with a polynucleotide encoding secretory component (SC) to form an SC transfected Ig producing cell, and culturing the SC transfected Ig producing cell so as to produce secretory Ig molecules.
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| Background / Summary: |
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| Drawing Descriptions: |
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| Description: |
Show description
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| Foreign References: |
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| Other Abstract Info: |
CHEMABS 130(07)080348K
DERABS C1999-080950
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| Other References: |
Michetti, et al. (1991) Immunology of Milk an d the Neonate 310:183-185.
Kracji, et al. (1989) Biochemical and Biophysical Research Communications 158(3):783-789.
Mazanec, et al., (1987) J. Virol. 61:2624.
(3 pages)
Cited by 7 patents
Mazanec, et al. (1989) J. Immunol. 142:4275.
(7 pages)
Cited by 3 patents
Renegar, et al. (1991) J. Immunol. 146:1972.
Brown, et al. (1970) J. Clin. Invest. 49:1374.
Lindh, (1975) J. Immunol. 114:284.
(3 pages)
Cited by 5 patents
Hirt, et al. (1993) Cell 74:245-255.
(11 pages)
[ISI abstract]
Lullau, et al. (1996) J. Biol. Chem. 271:16300.
(10 pages)
Cited by 3 patents
[ISI abstract]
Ma, et al. (1995) Science 268:716-719.
(4 pages)
Cited by 22 patents
[ISI abstract]
J.F. Piskurich, et al. (1995) J. Immunol. 154:1735-1747.
(13 pages)
Cited by 6 patents
[ISI abstract]
Ma, et al. (1998) Nature Med. 4(5):601-606.
(6 pages)
[ISI abstract]
Tamer, et al. (1993) Mol. Immunol. 30(4):413-421.
(9 pages)
[ISI abstract]
Chintalacharuvu, et al. (1996) J. Immunol. 157:3443.
(7 pages)
Cited by 2 patents
[ISI abstract]
Mostov, et al. (1993) Meth. Enzymol. 98:40.
Scheinderman, et al. (1989) Proc. Natl. Acad. Sci. USA 86:7561.
Knight, et al. (1975) J. Immunol. 115:595.
(4 pages)
Weltzin, et al.(1989) J. Cell Biology 108:1673-1685.
(13 pages)
Cited by 2 patents
Winner et al. (1991) Infect. Immun. 59:977.
(6 pages)
Cited by 6 patents
[ISI abstract]
Coloma et al. (1992) J. Immunol. Meth. 152:89.
(16 pages)
Cited by 19 patents
[ISI abstract]
Chintalacharuvu et al. (1991) J. Cell Physiol. 148:35.
(13 pages)
[ISI abstract]
Chintalacharuvu et al. (1993) Mol. Immunol. 30:19.
(8 pages)
[ISI abstract]
Oravax Report.
Chintalacharuvu and Morrison (1997) Proc. Natl. Acad. Sci. USA 94: 6364-6368.
(5 pages)
[ISI abstract]
Copy of International Search Report cited in Applicants' corresponding PCT Patent Application Serial No. PCT/US98/11975.
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| Continuity Data: |
| Application Number | Filed | Notes |
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US2001000950294 | 2001-09-10 | is a
division of |
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>US1998000095385<
| 1998-06-10 |
(granted)
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US6300104 issued 2001-10-09 Secretory immunoglobulin produced by single cells and methods for making and using same
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US1998000095385 | 1998-06-10 | is a
non-provisional of provisional |
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US1997000050969P
| 1997-06-19 |
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