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Title: US6326361: Gangliosides with immunosuppressive activity
[ Derwent Title ]

Country: US United States of America

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10 pages

 
Inventor: Ladisch, Stephan; Pacific Palisades, CA

Assignee: The Regents of the University of California, Los Angeles, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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Published / Filed: 2001-12-04 / 1993-06-02

Application Number: US1993000071304
IPC Code: Advanced: A61K 31/70; C07H 15/10;
Core: C07H 15/00; more...
IPC-7: A61K 9/127; A61K 31/715; C07H 15/00;

ECLA Code: A61K31/70; C07H15/10D2;

U.S. Class: Current: 514/054; 424/450; 536/004.1; 536/017.2; 977/773; 977/795; 977/907; 977/918; 977/926;
Original: 514/054; 424/450; 536/004.1; 536/017.2;

Field of Search: 514/054 424/450 536/4.1,17.2

Priority Number:
1993-06-02  US1993000071304
1992-09-28  US1992000951891
1991-03-29  US1991000677437

Abstract: A method for suppressing immune responses in animals by administering gangliosides to the animal. Gangliosides having terminal sialic acid groups are disclosed as being especially effective as immunosuppressive agents. The especially effective immunosuppressive gangliosides include GM4 and GM5. Ganglioside compositions for use in suppressing immune responses are also disclosed.

Primary / Asst. Examiners: Fonda, Kathleen Kahler;

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Related Applications:
Application Number Filed Patent Pub. Date  Title
US1992000951891 1992-09-28       
US1991000677437 1991-03-29       


       
Parent Case:     This is a continuation of Ser. No. 07/951,891 filed on Sep. 28, 1992, now abandoned, which is a continuation of Ser. No. 07/677,437 filed on Mar. 29, 1991, also abandoned.

Designated Country: CA EP JP 

Family: Show 2 known family members
First Claim:
Show all 7 claims		 What is claimed is:     1. A method for suppressing an immune response in an animal which comprises administering to the animal an immunosuppressively effective amount of a ganglioside wherein said ganglioside is GM4.

Background / Summary: Show background / summary

Drawing Descriptions: Show drawing descriptions

Description: Show description

       
U.S. References: Go to Result Set: All U.S. references   |  No patents reference this one   |   Backward references (5)   |   Citation Link

Buy
PDF		 Patent  Pub.Date  Inventor Assignee   Title
Buy PDF- 7pp US4327710  1982-05 De Loach et al.  The United States of America as represented by the Secretary of Agriculture Process for encapsulating additives in resealed erythrocytes for disseminating chemicals via the circulatory system
Buy PDF- 9pp US4730058  1988-03 Ogawa et al.  Mect Corporation Sialosylceramides and production method thereof
Buy PDF- 5pp US4914085  1990-04 Ochi  Otsuka Pharmaceutical Co., Ltd. Antirheumatic agent
Buy PDF- 6pp US5173219  1992-12 Kim  Research Development Foundation Uniform spherical multilamellar liposomes of defined and adjustable size distribution
Buy PDF- 9pp US5229376  1993-07 Alving et al.  The United States of America as represented by the Secretary of the Army Encapsulated plant-derived phosphatidylinositol (PI) compositions for the prevention of mitogenically induced cell proliferation
       
Foreign References: None

Other Abstract Info: CHEMABS 118(03)016307W DERABS C1992-365983

Other References:
  • Agarwal et al; J. Immunol. 107(5):1448-1456 (1971).* Cited by 2 patents
  • Miceli et al; ACTA Psychiat. Scand. 55:102-110 (1977).* (9 pages) Cited by 8 patents
  • Yates et al; Chemical Abstracts 93: 112178r (1980).*
  • Whisler et al; J. Immunol. 125(5): 2106-2111 (1980).* (6 pages) Cited by 10 patents
  • Hakomori; Ann. Rev. Biochem. 50: 733-764 (1981).* (32 pages) Cited by 13 patents
  • Ladisch et al; Cancer RES. 43: 3808-3813 (1983).* (6 pages) Cited by 4 patents
  • Ladisch et al; J. Clin. Invest. 74:2074-2081 (1984).* (8 pages) Cited by 4 patents
  • Sugimoto et al; Garb. Res. 156: cl-c5 (1986).*
  • Yates et al; ACS Symp. Series 128(Cell Surface Glycolipids) pp 419-433 (1980).*
  • Hakomori et al; Adv. Exp. Med. Biol. 125: 247-261 (1980).*
  • Nagai et al; 1st Intnat'l Symp. Hertie Found., Frankfurt "Search of the Case of MS and Other Chronic Diseases of the CNS" pp 127-138 (1980) Vorlag-Chemie.*
  • Jackson et al; Cellular Immunology 104:169-181 (1987).* (13 pages)
  • Cavaillon et al; Eur. J. Immunol. 16:1009-1012 (1986).* (4 pages) Cited by 5 patents
  • Ladisch et al; J. Clin. Invest. 79:1879-1882 (Jun. 1987).* (4 pages) Cited by 2 patents
  • Prokazova et al, Eur. J. Biochem. 172:1-6 (1988).* (6 pages) Cited by 10 patents
  • Floutsis et al; Int. J. Cancer 43:6-9 (1989).* (4 pages) Cited by 3 patents
  • Hachida et al; Transplant. Proc. 22(4):1663-1665 (Aug. 1990).* (3 pages) Cited by 3 patents
  • Dillman et al; Molecular Biotherapy 4:117-121 (Sep. 1992). (5 pages) Cited by 10 patents [ISI abstract]


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