Work Files Saved Searches
   My Account                                                  Search:   Quick/Number   Boolean   Advanced   Derwent    Help   


 The Delphion Integrated View
  Buy Now:   Buy PDF- 42pp  PDF  |   File History  |   Other choices   
  Tools:  Citation Link  |  Add to Work File:    
  View:  Expand Details   |  INPADOC   |  Jump to: 
  Go to:  Derwent  
 Email this to a friend  Email this to a friend 
       
Title: US6383760: Transcriptionally regulated G protein-coupled receptor
[ Derwent Title ]
>> View Certificate of Correction for this publication

Country: US United States of America

View Images High
Resolution

 Low
 Resolution

 
42 pages

 
Inventor: Weng, Zhigang; Cambridge, MA
Witte, Owen N.; Sherman Oaks, CA

Assignee: The Regents of the University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
 News, Profiles, Stocks and More about this company

Published / Filed: 2002-05-07 / 2000-11-09

Application Number: US2000000710481
IPC Code: Advanced: A61K 45/00; A61K 48/00; A61P 35/02; A61P 43/00; C07K 14/705; C12N 15/09; C12N 15/12; C12P 21/02; G01N 33/15; G01N 33/50; G01N 33/53; G01N 33/566; G01N 33/74; A61K 38/00; A61K 39/00;
Core: A61P 35/00; C07K 14/435; more...
IPC-7: C12N 15/12; C12N 15/63; G01N 33/50;

ECLA Code: C07K14/705;

U.S. Class: Current: 435/007.1; 435/007.2; 435/007.21; 435/069.1; 435/252.3; 435/325; 435/456; 530/300; 530/350; 536/023.1; 536/024.3;
Original: 435/007.1; 435/007.2; 435/007.21; 435/069.1; 435/325; 435/172.3; 435/252.3; 536/024.3; 536/023.1; 530/300; 530/350;

Field of Search: 435/7.2,7.21,7.1,69.1,325,172.3,252.3 536/24.3,23.1 530/300,350

Priority Number:
2000-11-09  US2000000710481
1998-07-17  US1998000120025
1997-11-13  US1997000969815

Abstract: A G protein-coupled receptor (GPCR), called G2A, whose expression is regulated and functions at the G2/M checkpoint to ensure properly controlled duplication of hematopoietic cells. The receptor is found predominantly in hematopoietic cells and tissues and functions as a tumor suppressor gene and induces cell cycle arrest. This receptor may play an important role in regulating the proliferation and differentiation of hematopoietic cells. Regulation of receptor activity has several therapeutic applications.

Attorney, Agent or Firm: Gates & Cooper LLP ;

Primary / Asst. Examiners: Eyler, Yvonne; Basi, Nirmal S.
Maintenance Status: CC Certificate of Correction issued
View Certificate of Correction

INPADOC Legal Status: Show legal status actions          Buy Now: Family Legal Status Report

       
Related Applications:
Application Number Filed Patent Pub. Date  Title
US1998000120025 1998-07-17    2001-04-10  Transcriptionally regualted G protein-coupled receptor
US1997000969815 1997-11-13    2001-03-27  Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells


       
Parent Case:

RELATED APPLICATIONS
    This present application is a continuation of U.S. patent application Ser. No. 09/120,025 filed Jul. 17, 1998, now U.S. Pat. No. 6,214,562, which is a continuation-in-part of U.S. patent application Ser. No. 08/969,815, filed on Nov. 13, 1997, now U.S. Pat. No. 6,207,412.

Designated Country: AL AM AP AZ BA BB BG BR BY CN CU CZ EA EE GE GH GM HR HU ID IL IS KE  AT BE CH CY DE DK ES FI FR GB GR IE IT 

Family: Show 17 known family members
First Claim:
Show all 10 claims		 What is claimed is:     1. A method of identifying a compound which specifically binds a G protein coupled receptor G2A shown in SEQ ID NO: 2 or 4, where said G2A is capable of transcriptional regulation by a tyrosine kinase, comprising the steps of:
  • contacting said G2A with a test compound; and
  • determining whether said test compound binds to said G2A so that a compound which binds to said G2A can be identified, wherein a test compound which binds said G2A may be further screened for activation of said G2A.
    •


Background / Summary: Show background / summary

Drawing Descriptions: Show drawing descriptions

Description: Show description

       
U.S. References: Go to Result Set: No U.S. references   |  No patents reference this one   |   Backward references (0)

       
Foreign References: None

Other Abstract Info: CHEMABS 131(02)014841K CHEMABS 134(20)275755F DERABS C1999-338006

Other References:
  • Afar et al., "Differential Complementation of . . . c-Myc", Science, 164:424-426, 1994. (3 pages) Cited by 4 patents [ISI abstract]
  • Afar et al., "Signaling by ABL . . . D1", Proc. Natl. Acad. Sci. USA, 92:9540-9544, 1995. (5 pages) Cited by 4 patents [ISI abstract]
  • Alkhatib et al., "CC CKR5: A RANTES . . . HIV-1", Science, 272:1955-1958, 1996. (4 pages) Cited by 63 patents [ISI abstract]
  • Arvanitakis et al., Human herpesvirus KSHV . . proliferation, NATURE, 385:347-350, 1997. (4 pages) Cited by 12 patents [ISI abstract]
  • Bouvier, M. et al., "Dynamic Palmitoylation . . . cells", Methods in Enzym., Acad Press pp. 300-314, 1995. (15 pages) Cited by 11 patents [ISI abstract]
  • Braun et al., "Identification of Target . . . Analysis", Molecular and Cellular Biology, 15(8):4623-4630, 1995. (8 pages) Cited by 24 patents [ISI abstract]
  • Choe et al., "The β-Chemokine Receptos . . Isolates", Cell, 85:1135-1148, 1996. (14 pages) Cited by 55 patents [ISI abstract]
  • Choi et al., "Identification of a Putative . . . Cells", Cellular Immunology, 168:78-84, 1996. (7 pages) Cited by 5 patents [ISI abstract]
  • Davis, R.J., "Transcriptional Regulation by MAP Kinases", Molecular Repr. and Devel., 42:459-467, 1995. (9 pages) Cited by 5 patents [ISI abstract]
  • Deng et al., "Identification of a major . . . HIV-1", Nature, 381:661-666, 1996. (6 pages) Cited by 107 patents [ISI abstract]
  • Doranz et al., "A Dual-Tropic Primary . . . Cofactors", Cell, 85:1148-1158, 1996.
  • Dragic et al., "HIV-1 entry into . . . CC-CKR-5", Nature, 381:667-673, 1996. (7 pages) Cited by 96 patents [ISI abstract]
  • Feng et al., "HIV-1 Entry Cofactor . . Receptor", Science, 272:872-877, 1996. (6 pages) Cited by 96 patents [ISI abstract]
  • Forster et al., "A Putative Chemokine . . . Spleen", Cell, 87:1037-1047, 1996. (11 pages) Cited by 6 patents [ISI abstract]
  • Fu, M.L.X., "Characterization . . . study", Molecular and Cellular Biochemistry, 163/164:343-347, 1996. (5 pages) Cited by 5 patents [ISI abstract]
  • Goga et al., "Alternative Signals to . . . Oncogene", Cell, 82:981-988, 1995. (8 pages) Cited by 5 patents [ISI abstract]
  • Hubank et al., "Identifying differences in . . . cDNA", Nucleic Acids Research, 22(25):5640-5648, 1994. (9 pages) Cited by 45 patents [ISI abstract]
  • Koshiba et al., "Transient up-regulation . . . thymocytes", Proc. Natl. Acad. Sci. USA, 94:831-836, 1997. (6 pages) Cited by 5 patents [ISI abstract]
  • Kurzrock et al., "The Molecular . . . Leukemias", The New Eng. Journal of Med, 319(15):990-998, 1988. (9 pages) Cited by 7 patents
  • Libert, F. et al., "Selective Amplification . . . Family", Science, 244:569-572, 1989. (4 pages) Cited by 86 patents
  • Lugo et al., "The BCR0ABL . . . v-myc", Molecular and Cellular Biology, 9(3):1263-1270, 1989. (8 pages) Cited by 8 patents
  • McLaughlin et al., "Alternative Forms . . Cells", Molecular and Cellular Biology, 9(5):1866-1874, 1989. (9 pages) Cited by 10 patents
  • Muller et al., "BCR First . . . Leukemias", Molecular and Cellular Biology, 11(4):1785-1792, 1991. (8 pages) Cited by 31 patents [ISI abstract]
  • Murphy, P.M., "The Molecular . . . Receptors", Annu. Rev. Immunol., 12:593-633, 1994. (41 pages) Cited by 74 patents [ISI abstract]
  • Pear et al., "Production of high-titer . . . transfection", Proc. Natl. Acad. Sci. USA,90:8392-8396, 1993. (5 pages) Cited by 77 patents [ISI abstract]
  • Pendergast et al., "BCR-ABL-Induced . . . Protein", Cell, 75:175-185, 1993. (11 pages) Cited by 16 patents [ISI abstract]
  • Schneider et al., "Genes Specifically . . . Cells", Cell, 54:787-793, 1988. (7 pages) Cited by 17 patents
  • Strader et al., "The family . . . receptors", The FASEB Journal, 9:745-754, 1995. (10 pages) Cited by 18 patents [ISI abstract]
  • Strader et al., "Structure and Function . . . Receptors", Annu. Rev. Biochem., 63:101-132, 1994. (32 pages) Cited by 15 patents [ISI abstract]
  • Tsukada et al., "Deficient Expression . . . Agammaglobulinemia", Cell, 71:279-290, 1993. (12 pages) Cited by 11 patents [ISI abstract]
  • Lisitsyn et al., "Cloning the Differences . . . Genomes", Science, 259:946-951, 1993. (6 pages) Cited by 102 patents [ISI abstract]


    • Inquire Regarding Licensing

    Powered by Verity
    Plaques from Patent Awards      Gallery of Obscure PatentsNominate this for the Gallery...

    Thomson Reuters Copyright © 1997-2010 Thomson Reuters 
    Subscriptions  |  Web Seminars  |  Privacy  |  Terms & Conditions  |  Site Map  |  Contact Us  |  Help