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Title: US6514696: Transcriptionally regulated G protein-coupled receptor G2A
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Country: US United States of America

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59 pages

 
Inventor: Weng, Zhigang; Brookline, MA
Witte, Owen N.; Sherman Oaks, CA

Assignee: The Regents of The University of California, Oakland, CA
other patents from UNIVERSITY OF CALIFORNIA, THE REGENTS OF (599425) (approx. 4,840)
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Published / Filed: 2003-02-04 / 2000-04-20

Application Number: US2000000553875

IPC Code: Advanced: A61K 45/00; A61K 48/00; A61P 35/02; A61P 43/00; C07K 14/705; C12N 15/09; C12N 15/12; C12P 21/02; G01N 33/15; G01N 33/50; G01N 33/53; G01N 33/566; G01N 33/74; A61K 38/00; A61K 39/00;
Core: A61P 35/00; C07K 14/435; more...
IPC-7: C12N 15/12; C12N 15/63; C12Q 1/68; G01N 33/50;

ECLA Code: C07K14/705; G01N33/74;

U.S. Class: Current: 435/006; 435/069.1; 435/091.2; 435/252.3; 435/320.1; 435/455; 530/300; 530/350; 536/023.1; 536/024.3;
Original: 435/006; 435/069.1; 435/091.2; 435/172.3; 435/252.3; 435/320.1; 536/023.1; 536/024.3; 530/300; 530/350;

Field of Search: 435/006,69.1,91.2,172.3,252.3,320.1 536/23.1,24.3 530/300,350

Priority Number:
2000-04-20  US2000000553875
1998-07-17  US1998000120025
1997-11-13  US1997000969815

Abstract: A G protien-coupled receptor (GPCR), called G2A, whose expression is regulated and functions at the G2/M checkpoint to ensure properly controlled duplication of hematopietic cells. The receptor is found predominantly in hematopietic cells and tissues and functions as a tumor suppressor gene, induces cell cycle arrest and integrates diverse signals by modulation of cytoskeletal architecture.

Attorney, Agent or Firm: Gates & Cooper LLP ;

Primary / Asst. Examiners: Eyler, Yvonne; Basi, Nirmal S

Maintenance Status: CC Certificate of Correction issued
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Related Applications: Go to Result Set: 1 patent(s) that list this one as related
Application Number Filed Patent Pub. Date  Title
US1998000120025 1998-07-17    2001-04-10  Transcriptionally regualted G protein-coupled receptor
US1997000969815 1997-11-13    2001-03-27  Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells


       
Parent Case:

RELATED APPLICATIONS
    This present application is a continuation-in-part of U.S. patent application Ser. No. 09/120,025, filed Jul. 17, 1998, now U.S. Pat. No. 6,214,562, which is a continuation-in-part of U.S. patent application Ser. No. 08/969,815, filed on Nov. 13, 1997, now U.S. Pat. No. 6,207,412.

Designated Country: AE AG AL AM AP AT AZ BA BB BG BR BY BZ CH CN CO CR CU CZ DE DK DM DZ EA EE ES FI GB GD GE GH GM HR  BE CY FR GR 

Family: Show 18 known family members

First Claim:
Show all 3 claims
What is claimed is:     1. A method for determing the presence of G2A in a biological sample comprising contacting the sample with a polynucleotide that specifically hybridizes to a G2A nucleotide sequence shown in SEQ ID NO:1 or 3 and detecting the presence of a hybridization complex formed by the hybridization of the polynucleotide with G2A nucleotide in the sample, wherein the presence of a hybridization complex indicates the presence of G2A polynucleotide within the sample.

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U.S. References: Go to Result Set: No U.S. references   |  No patents reference this one   |   Backward references (0)

       
Foreign References:
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Publication Date IPC Code Assignee   Title
Buy PDF WO9925830 1999-05  C12N 15/12 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA TRANSCRIPTIONALLY REGULATED G PROTEIN-COUPLED RECEPTOR 


Other Abstract Info: CHEMABS 131(02)014841K CHEMABS 134(20)275755F CHEMABS 135(24)340697A CHEMABS 136(22)337370D DERABS C1999-338006 DERABS C2002-062048

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  • Continuity Data:
    Application Number Filed Notes

    US2001000796266 2001-02-28  is a continuation in part of
    >US2000000553875<  2000-04-20   (pending) [presumed granted]
         US6514696 issued 2003-02-04   Transcriptionally regulated G protein-coupled receptor G2A

    >US2000000553875< 2000-04-20  is a continuation in part of
    US1998000120025  1998-07-17   (granted)
         US6214562 issued 2001-04-10   Transcriptionally regualted G protein-coupled receptor

    US1998000120025 1998-07-17  is a continuation in part of
    US1997000969815  1997-11-13   (granted)
         US6207412 issued 2001-03-27   Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells


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