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Title: US20060035899A1: Use of cysteine derivatives for the preparation of a medicament intended to treat pathologies which result from the formation of the heterotrimeric G protein
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Country: US United States of America

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22 pages

 
Inventor: Prevost, Gregoire; Antony, France
Lonchampt, Marie-Odile; Chevilly-Larue, France
Gordon, Thomas; Medway, MA, United States of America

Assignee: SCRAS
other patents from SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (682867) (approx. 144)
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Published / Filed: 2006-02-16 / 2005-09-09

Application Number: US2005000222601

IPC Code: Advanced: A61K 31/198; A61K 31/223; A61K 31/4164; A61K 31/421; A61K 31/426; A61K 31/495; A61K 31/496; A61K 31/498; A61K 31/4985; A61P 3/04; A61P 3/06; A61P 3/10; A61P 5/00; A61P 9/12; A61P 15/00; A61P 25/02; A61P 25/28; A61P 31/12; A61P 35/00; A61P 37/02; C07D 233/64; C07D 241/04; C07D 263/32; C07D 277/28; C07D 417/06; C07D 487/04; C12N 9/88;

ECLA Code: C07D487/04; A61K31/223; A61K31/498; A61K31/4985; C12N9/88;

U.S. Class: 514/249;

Priority Number:
1998-07-08  FR1998000008731

Abstract:     The invention relates to the use of cysteine derivatives for preparing a medicament intended to treat diseases which result from the formation of the heterotrimeric G protein. These diseases include in particular diseases linked to the following biological functions or disorders: smell, taste, perception of the light, neurotransmission, neurodegeneration, endocrine and exocrine gland functions, autocrine and paracrine regulation, arterial tension, embryogenesis, benign cell proliferation, oncogenesis, viral infection, immunological functions, diabetes, obesity, and benign :and malign proliferative diseases. Said cysteine derivatives include in particular: bis-1,1'-[7-(2-amino-1-oxo-3-thiopropyl)-8-(cyclohexylmethyl)-2-(2-methoxyphenyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazine disulphide (I), and bis-1,1'-7-(2-amino-1-oxo-3-thiopropyl-(2-(1-naphtyl)-8-(2-methylpropyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazin-7-yl) disulphide (II).

Attorney, Agent or Firm: Charles A. Muserlian c/o Hedman and Costigan; 1185 Avenue of the Americas , New York , NY 10036 United States of America

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First Claim:
Show all 6 claims
    1 - 12 . (canceled)

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U.S. References: Go to Result Set: No U.S. references   |  No patents reference this one   |   Backward references (0)

       
Continuity Data:
Application Number Filed Notes

>US2005000222601< 2005-09-09  is a division of
US2003000356862  2003-02-03   (pending) [presumed granted]
     US7034025 issued 2006-04-25   Use of cysteine derivatives for the preparation of a medicament intended to treat pathologies which result from the formation of the heterotrimeric G protein

US2003000356862 2003-02-03  is a division of
US2001000743208  2001-01-04   (granted)   PCT/FR99/01609
     US6544995 issued 2003-04-08   Use of cysteine derivatives for preparing a medicine for treating pathologies resulting from the formation of heterotrimeric G protein


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