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 Title: |
WO02100250A2:
WIT 3.0, A NOVEL GENE TO CONTROL SOFT TISSUE WOUND HEALING[French]
[ Derwent Title ]
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Country:
Kind: |
WO World Intellectual Property Organization (WIPO)
A2 INTERNATIONAL APPLICATION PUBLISHED WITHOUT INTERNATIONAL SEARCH REPORT or INTERNATIONAL APPLICATION PUBLISHED WITH DECLARATION UNDER ARTICLE 17 (2) (A) i
(See also:
WO02100250C1 )
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| Inventor: |
NISHIMURA, Ichiro; 10961 Rose Avenue, No. 5, Los Angeles, CA 90034, United States of America
SUKOTJO, Cortino; 2511 Westwood Boulevard, Los Angeles, CA 90064, United States of America
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| Assignee: |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, 1111 Franklin Street, 5th floor, Oakland, CA 94607-5200, United States of America
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| Published / Filed: |
2002-12-19
/ 2002-06-12
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| Application Number: |
WO2002US0018828
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| IPC Code: |
Advanced:
A61K 31/711;
A61K 31/7125;
A61K 38/00;
A61K 48/00;
A61P 1/02;
A61P 17/02;
C07K 14/47;
C12N 1/15;
C12N 1/19;
C12N 1/21;
C12N 5/10;
C12N 15/09;
Core:
A61P 1/00;
A61P 17/00;
C07K 14/435;
more...
IPC-7:
C07H 21/02;
C12N 1/20;
C12N 15/00;
C12P 21/06;
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| ECLA Code: |
C07K14/47;
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| Priority Number: |
| 2001-06-12 |
US2001000297720P |
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| Abstract: |
The present invention provides a method of treatment to improve wound healing and to minimize/prevent abnormal scarring caused by tissue contraction and fibrosis formation by providing a specific gene, Wit 3.0 alpha and beta sequences that is differentially expressed in wounded oral mucosa cells, relative to their decreased expression in non-wounded oral mucosa cells. One aspect of the invention is a method to treat soft tissue wound using anti-sense nucleic acid technologies. Another aspect of the present invention is a method to treat soft tissue wound using sense nucleic acid technologies. These methods can employ a complimentary nucleic acid sequence that is greater than 85% identity to Wit 3.0 alpha and/or beta sequences or greater than 90% identity to the deduced amino acids thereof.
[French]
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| Attorney, Agent or Firm: |
FARBER, Michael, B. ; Oppenheimer Wolff & Donnelly LLP, Suite 3800, 2029 Century Park East, Los Angeles, CA 90067-3024
United States of America
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| INPADOC Legal Status: |
Show legal status actions
Family Legal Status Report
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| Designated Country: |
AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW,
European patent:
AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR,
OAPI patent:
BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG,
ARIPO patent:
GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW,
Eurasian patent:
AM AZ BY KG KZ MD RU TJ TM
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| Family: |
Show 8 known family members
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First Claim:
Show all claims |
WE CLAIM:
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Description
Expand description |
+ WIT 3.0, A NOVEL GENE TO CONTROL SOFT TISSUE WOUND HEALING
+ BACKGROUND OF THE INVENTION
Field of Invention
+ Brief Description of the Drawings
[00321 Detailed description of the preferred embodiment of the invention will be made with
+ DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0043] This description is not to be taken in a limiting sense, but is made merely for the
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| Other Abstract Info: |
DERABS C2003-156901
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