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 Title: |
WO9104034A1:
TOPICAL PREPARATION FOR TREATMENT OF APHTHOUS ULCERS AND OTHER LESIONS
[ Derwent Title ]
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Country:
Kind: |
WO World Intellectual Property Organization (WIPO)
A1 INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT i
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| Inventor: |
PEHRSON, David, W., Sr.;
ROMANOWSKY, Michael, P.;
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| Assignee: |
PEHROM PHARMACEUTICAL CORPORATION
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| Published / Filed: |
1991-04-04
/ 1990-09-13
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| Application Number: |
WO1990US0005260
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| IPC Code: |
Advanced:
A61K 9/00;
A61K 31/70;
A61K 47/00;
IPC-7:
A61K 31/70;
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| ECLA Code: |
A61K9/00M3; A61K9/00M18D; A61K31/70; A61K31/7135;
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| Priority Number: |
| 1989-09-15 |
US1989000407813 |
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| Abstract: |
Aphthous ulcers and other lesions of the mucosal, submucosal, epidermal, dermal or subcutaneous tissue are treated by a method comprising administering to a patient suffering from such lesion a topical preparation containing sucralfate as an essential ingredient. The invention is also drawn to a preparation comprising sucralfate as an essential ingredient, and a method for preparing the same. The sucralfate is combined with an appropriate pharmaceutical medium to form a homogeneous mixture which can then be dispersed in other media to form a preparation useful for topical application to the lesion.
[French]
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| INPADOC Legal Status: |
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Family Legal Status Report
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| Designated Country: |
AT AU BE BG BR CA CH DE DK ES FI FR GB HU IT JP KR LU NL NO RO SE SU
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| Family: |
Show 6 known family members
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First Claim:
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CLAIMS
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Description
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+ TOPICAL PREPARATION FOR TREATMENT OF APHTHOUS ULCERS
AND OTHER LESIONS
+ BACKGROUND
There are several types of lesions of mucosal, submucosal, epidermal, dermal and subcutaneous tissue and various other inflammatory processes for which no effective cure has been found. These include aphthous ulcers, lesions of the pharynx and esophagus, stomatitis, gingivo-stomatitis, cheilosis, ulcerative colitis, venous stasis ulcers, lesions of the nasal passages, decubitus ulcers, and other types of lesions or inflammation of the mucosal, submucosal, dermal, epidermal, or subcutaneous tissue. The present invention has particular utility in the treatment of aphthous ulcers and other oral lesions and will be described in connection with such utility, although utility for the treatment of other types of lesions and inflammations is also indicated.
+ SUMMARY OF THE INVENTION
The present invention relates to a topical preparation which resolves aphthous ulcers and in most cases cures the lesion within 24-48 hours. Modified forms of the preparation are used to effectively treat esophagitis, chemically-induced micro-ulcerations of the pharynx and esophagus, stomatitis, gingivo-stomatitis, cheilosis, second-degree burns of the mucosal tissue, decubitus ulcers, and ulcerative colitis. The invention is also an -effective treatment for other lesions of the mucosal, submucosal, epidermal, dermal, and subcutaneous tissues.
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