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 Title: |
WO9400552A1:
FULLERENE COATED SURFACES AND USES THEREOF
[ Derwent Title ]
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Country:
Kind: |
WO World Intellectual Property Organization (WIPO)
A1 INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT i
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| Inventor: |
RICHMOND, Robert, C.;
GIBSON, Ursula, J.;
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| Assignee: |
THE TRUSTEES OF DARTMOUTH COLLEGE
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| Published / Filed: |
1994-01-06
/ 1993-06-14
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| Application Number: |
WO1993US0005680
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| IPC Code: |
Advanced:
C12M 1/40;
C12N 5/00;
C12N 15/87;
Core:
more...
IPC-7:
C12M 3/04;
C12N 5/00;
C12N 11/02;
C12N 11/06;
C12N 15/00;
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| Priority Number: |
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| Abstract: |
Substrates having a surface coated with fullerene and a substance attached thereto are disclosed. Cell culture substrates having a fullerene-coated surface are useful in methods of growing cells on the fullerene-coated surface. Methods of preparing cell culture substrates for cell attachment and growth by coating a surface with fullerene are provided. Cells can be grown on a fullerene-coated surface in the presence of a substance such as a cytokine, growth hormone or a drug, to evaluate the interaction between the substance and the cells. Methods for increasing cell membrane permeability and for introducing a substance, such as a DNA or RNA vector, into a cell are also provided.
[French]
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| INPADOC Legal Status: |
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Family Legal Status Report
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| Designated Country: |
AT BE CA CH DE DK ES FR GB GR IE IT JP LU MC NL PT SE
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| Family: |
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First Claim:
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11.A substrate comprising a fullerene-coated surface having a substance attached to the fullerene -coated surface, 2s A substrate of claim 1 wherein the fullerene comprises C60# C70, or a mixture Of C60 and C70,
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Description
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+ FULLERENE MATED SURFACES AND USES THMMF
+ BACKGROUND OF THE INVENTION
As a class, the recently discovered-third allotropic form of carbon is termed fullerenes, and the prototypical form of this class is a spherical hollow molecule containing 60 carbon atoms, 2*..e,,, C60, that is termed buckminsterfullerene (Kratschmer, W., et al., Nature 347:354-357 (1990); Ajie, H.
+ SUMMARY OF THE INVENTION
+ Brief Description of the Drawing
+ DETAILED DESCRIPTION OF THE INVENTION
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